Observational studyNeuropsychology2023
Can mild traumatic brain injury alter cognition chronically? A LIMBIC-CENC multicenter study.
Observational study in Neuropsychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Serum neutrophil extracellular trap-related biomarkers for identifying cognitive impairment after mild traumatic brain injury.Irish journal of medical science · 2026Article
- Plasma Biomarkers, Brain Volume, and Cognitive Performance in Service Members and Veterans With mTBI: A LIMBIC-CENC Study.JAMA network open · 2026Article
- Associations among aerobic physical activity, mild traumatic brain injury history, and health-related quality of life in military service members and Veterans: A LIMBIC-CENC study.PM & R : the journal of injury, function, and rehabilitation · 2026Article
- Article
- Mediators of epilepsy risk after traumatic brain injury: A 20-year U.S. veteran cohort study.Epilepsia · 2025Article
- Peritraumatic Context and Long-Term Outcomes of Concussion.JAMA network open · 2025Article
- Article
- Traumatic Brain Injury and Risk of Incident Comorbidities.JAMA network open · 2024Article
- Neuropsychological Profiles of Deployment-Related Mild Traumatic Brain Injury: A LIMBIC-CENC Study.Neurology · 2024Article
- Cognitive Impairment following Mild Traumatic Brain Injury (mTBI): A Review.Medicina (Kaunas, Lithuania) · 2024Review
- Blast-related mild TBI: LIMBIC-CENC focused review with implications commentary.NeuroRehabilitation · 2024Review
- Long-term resting EEG correlates of repetitive mild traumatic brain injury and loss of consciousness: alterations in alpha-beta power.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
14 authors at 9 institutions in 1 country.
Funding
Abstract
objectiveWhile outcome from mild traumatic brain injury (mTBI) is generally favorable, concern remains over potential negative long-term effects, including impaired cognition. This study examined the link between cognitive performance and remote mTBIs within the Long-term Impact of Military-relevant Brain Injury Consortium-Chronic Effects of Neurotrauma Consortium (LIMBIC-CENC) multicenter, observational study of Veterans and service members (SMs) with combat exposure.
methodBaseline data of the participants passing all cognitive performance validity tests (
resultsNeither of the mTBI positive groups differed from the mTBI negative control group on any of the cognitive domains in multivariable analyses. Findings were also consistently negative across sensitivity analyses (e.g., mTBIs as a continuous variable, number of blast-related mTBIs, or years since the first and last mTBI).
conclusionsOur findings demonstrate that the average veteran or SM who experienced one or more mTBIs does not have postacute objective cognitive deficits due to mTBIs alone. A holistic health care approach including comorbidity assessment is indicated for patients reporting chronic cognitive difficulties after mTBI(s), and strategies for addressing misattribution may be beneficial. Future study is recommended with longitudinal designs to assess within-subjects decline from potential neurodegeneration. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.