Evidence map›Paper›PMID 36174110›Full record

ArticleMolecular pharmaceutics2022

High-Contrast Detection of Somatostatin Receptor Subtype-2 for Fluorescence-Guided Surgery.

Servando Hernandez Vargas, Solmaz AghaAmiri, Sukhen C Ghosh, Michael P Luciano, Luis C Borbon, Po Hien Ear, James R Howe, Jennifer M Bailey-Lundberg, Gregory D Simonek, Daniel M Halperin and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Tissue-seeking dyes for in vivo applications.Smart molecules : open access · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Servando Hernandez VargasThe Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas77054, United States.ORCID 0000-0003-1614-7966
Solmaz AghaAmiriThe Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas77054, United States.
Sukhen C GhoshThe Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas77054, United States.
Michael P LucianoChemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland21702, United States.ORCID 0000-0002-1996-1587
Luis C BorbonDepartment of Surgery, University of Iowa Carver College of Medicine, Iowa City, Iowa52242, United States.
Po Hien EarDepartment of Surgery, University of Iowa Carver College of Medicine, Iowa City, Iowa52242, United States.
James R HoweDepartment of Surgery, University of Iowa Carver College of Medicine, Iowa City, Iowa52242, United States.
Jennifer M Bailey-LundbergDepartment of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas77030, United States.
Gregory D SimonekCenter for Laboratory Animal Medicine and Care, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas77030, United States.
Daniel M HalperinDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas77030, United States.
Hop S Tran CaoDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas77030, United States.
Naruhiko IkomaDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas77030, United States.
Martin J SchnermannChemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland21702, United States.ORCID 0000-0002-0503-0116
Ali AzhdariniaThe Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas77054, United States.ORCID 0000-0001-8000-907X
Brown Foundation · USThe University of Texas MD Anderson Cancer Center · USUniversity of Iowa · USFrederick National Laboratory for Cancer Research · USThe University of Texas Health Science Center at Houston · US

Funding

Project 4: New Approaches to Improving the Effectiveness of Radionuclide Targeted Treatments in Neuroendocrine TumorsP50CA174521 · NCI · UNIVERSITY OF IOWA · PI ODORISIO, THOMAS · 2015 to 2021
$13.2M
Washington University PDX Development and Trial Center - Evaluation of Abemaciclib in Combination with Olaparib in Ovarian Cancer and Breast Cancer Patient-derived Xenograft ModelsU54CA224083 · NCI · WASHINGTON UNIVERSITY · PI FENG CHEN · 2017 to 2026
$13.0M
NCI NIH HHS P50 CA174521NCI NIH HHS U54 CA224083
6 · The paper itself

Abstract

Dye design can influence the ability of fluorescently labeled imaging agents to generate tumor contrast and has become an area of significant interest in the field of fluorescence-guided surgery (FGS). Here, we show that the charge-balanced near-infrared fluorescent (NIRF) dye FNIR-Tag enhances the imaging properties of a fluorescently labeled somatostatin analogue.

Indexed as

NeoplasmsSurgery, Computer-AssistedAnimalsCell Line, TumorFluorescent DyesHumansMiceMice, NudeReceptors, SomatostatinFluorescent DyesReceptors, Somatostatincancer surgerydual labelingfluorescence-guided surgeryintraoperative imagingnear-infrared fluorescence imagingsomatostatin receptor

Identifiers

PMID36174110
PMCPMC9830638
OpenAlexW4297983595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.