SynthesisAge and ageing2022
Preprocedural muscle strength and physical performance and the association with functional decline or mortality in frail older patients after transcatheter aortic valve implementation: a systematic review and meta-analysis.
Synthesis in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 9 citations in OpenAlex.
- Prognostic Impact of Gait Speed Changes During Hospitalization in Patients Undergoing Transcatheter Aortic Valve Implantation.Circulation reports · 2026Article
- Impact of Extravalvular Remodeling on Wearable Smartwatch-Recorded Physical Activity in Patients Undergoing Transcatheter Aortic Valve Implantation for Severe Symptomatic Aortic Stenosis.Journal of the American Heart Association · 2026Article
- Comprehensive assessment of sarcopenia in patients with severe aortic stenosis undergoing transcatheter valve implantation.Journal of geriatric cardiology : JGC · 2026Article
- Relationship between nutrition status and muscle mass and its impact on 1-year mortality in patients with aortic stenosis undergoing transcatheter aortic valve implantation.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Perianesthesia Nurses' Perspectives Managing Frailty: A Qualitative Study.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses · 2026Article
- Multidimensional Frailty and Mortality in Transcatheter Aortic Valve Implantation Patients - Prognostic Value of the Kihon Checklist.Circulation reports · 2026Article
- Early Post-TAVI Physical Activity After Eccentric Training Compared to Standard Practice - Results of a Feasibility Study.Clinical interventions in aging · 2026Article
- Exercise-induced pulse pressure augmentation is positively associated with exercise capacity in patients after transcatheter aortic valve implantation.Frontiers in physiology · 2026Article
- Safety and effectiveness of oscillatory whole-body vibration training on exercise capacity and physical performance in aortic valve stenosis patients prior to transcatheter aortic valve implantation: a randomized clinical trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Article
- The Trajectory of Nutritional Status and Physical Activity before and after Transcatheter Aortic Valve Implantation.Nutrients · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA significant number of older patients planned for transcatheter aortic valve implantation (TAVI) experience a decline in physical functioning and death, despite a successful procedure.
objectiveTo systematically review the literature on the association of preprocedural muscle strength and physical performance with functional decline or long-term mortality after TAVI.
methodsWe followed the PRISMA guidelines and pre-registered this review at PROSPERO (CRD42020208032). A systematic search was conducted in MEDLINE and EMBASE from inception to 10 December 2021. Studies reporting on the association of preprocedural muscle strength or physical performance with functional decline or long-term (>6 months) mortality after the TAVI procedure were included. For outcomes reported by three or more studies, a meta-analysis was performed.
resultsIn total, two studies reporting on functional decline and 29 studies reporting on mortality were included. The association with functional decline was inconclusive. For mortality, meta-analysis showed that low handgrip strength (hazard ratio (HR) 1.80 [95% confidence interval (CI): 1.22-2.63]), lower distance on the 6-minute walk test (HR 1.15 [95% CI: 1.09-1.21] per 50 m decrease), low performance on the timed up and go test (>20 s) (HR 2.77 [95% CI: 1.79-4.30]) and slow gait speed (<0.83 m/s) (HR 2.24 [95% CI: 1.32-3.81]) were associated with higher long-term mortality.
conclusionsLow muscle strength and physical performance are associated with higher mortality after TAVI, while the association with functional decline stays inconclusive. Future research should focus on interventions to increase muscle strength and physical performance in older cardiac patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.