ArticleEuropean heart journal. Acute cardiovascular care2022
Cardiogenic shock severity and mortality in patients receiving venoarterial extracorporeal membrane oxygenator support.
Article in European heart journal. Acute cardiovascular care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Pooled it
- Prognostic impact of SCAI shock severity classes in AMI-related cardiogenic shock: A sub-study of the ECLS-SHOCK Trial.ESC heart failure · 2025Trial
- Early Lower Pulmonary Arterial Diastolic Pressure Monitored With Pulmonary Arterial Catheters Is Associated With Improved Survival During VA ECMO for Patients With Acute Cardiogenic Shock: A Propensity-Matched Study.JACC. Heart failure · 2026Article
- Left ventricular unloading during VA-ECMO for refractory cardiogenic shock: a target trial emulation multicenter analysis.Critical care (London, England) · 2026Article
- Hospital Costs Associated With Mechanical Left Ventricular Unloading Devices During VA ECMO for Adult Cardiogenic Shock.Artificial organs · 2026Article
- Acid-Base Status During Venoarterial Extracorporeal Membrane Oxygenator Support in Patients With Cardiogenic Shock.Journal of the American Heart Association · 2026Article
- Venoarterial extracorporeal membrane oxygenation in adults with cardiogenic shock.Frontiers in cardiovascular medicine · 2026Review
- ECMO management in cardiogenic shock-specialized versus non-cardiogenic shock-specialized centers: a registry-based analysis.BMC anesthesiology · 2025Article
- A simple VA-ECMO bundle in adult patients with cardiogenic shock: an analysis of ELSO registry.EClinicalMedicine · 2025Article
- Using a Cardiogenic Shock Classification System for Predicting Postcardiotomy Shock Mortality.JACC. Asia · 2025Article
- Risk factors influencing the prognosis of patients with acute myocardial infarction and cardiogenic shock undergoing extracorporeal membrane oxygenation therapy.Journal of cardiothoracic surgery · 2025Article
- Tailored Approach to Temporary Mechanical Circulatory Support for Cardiogenic Shock: Strategies to Facilitate Patient Mobilization.Current cardiology reports · 2025Review
- Acute kidney injury and cardiogenic shock severity for mortality risk stratification in patients supported with VA ECMO.ESC heart failure · 2024Article
- Hemodynamic management of cardiogenic shock in the intensive care unit.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Review
- Pulmonary Artery Pressures and Mortality During Venoarterial ECMO: An ELSO Registry Analysis.Circulation. Heart failure · 2024Article
- The use of venoarterial extracorporeal membrane oxygenation in cardiogenic shock: a narrative review.European heart journal open · 2024Article
- Comparative Analysis of Therapeutic Strategies in Post-Cardiotomy Cardiogenic Shock: Insight into a High-Volume Cardiac Surgery Center.Journal of clinical medicine · 2024Article
- Timing of Initiation of Extracorporeal Membrane Oxygenation Support and Outcomes Among Patients With Cardiogenic Shock.Journal of the American Heart Association · 2024Article
- Serial Assessment of Shock Severity in Cardiac Intensive Care Unit Patients.Journal of the American Heart Association · 2023Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
aimsShock severity predicts mortality in patients with cardiogenic shock (CS). We evaluated the association between pre-cannulation Society for Cardiovascular Angiography and Intervention (SCAI) shock classification and mortality among patients receiving venoarterial (VA) extracorporeal membrane oxygenation (ECMO) support for CS. METHODS AND
resultsWe included Extracorporeal Life Support Organization (ELSO) Registry patients from 2010 to 2020 who received VA ECMO for CS. SCAI shock stage was assigned based on hemodynamic support requirements prior to ECMO initiation. In-hospital mortality was analyzed using multivariable logistic regression. We included 12 106 unique VA ECMO patient runs with a median age of 57.9 (interquartile range: 46.8, 66.1) years and 31.8% were females; 3472 (28.7%) were post-cardiotomy. The distribution of SCAI shock stages at ECMO initiation was: B, 821 (6.8%); C, 7518 (62.1%); D, 2973 (24.6%); and E, 794 (6.6%). During the index hospitalization, 6681 (55.2%) patients died. In-hospital mortality increased incrementally with SCAI shock stage (adjusted OR: 1.24 per SCAI shock stage, 95% CI: 1.17-1.32, P < 0.001): B, 47.5%; C, 52.8%; D, 60.8%; E, 65.1%. A higher SCAI shock stage was associated with increased in-hospital mortality in key subgroups, although the SCAI shock classification was only predictive of mortality in non-surgical (medical) CS and not in post-cardiotomy CS.
conclusionThe severity of shock prior to cannulation is a strong predictor of in-hospital mortality in patients receiving VA ECMO for CS. Using the pre-cannulation SCAI shock classification as a risk stratification tool can help clinicians refine prognostication for ECMO recipients and guide future investigations to improve outcomes.
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