Evidence map›Paper›PMID 36173739›Full record

ArticleAging cell2022

Mistakes in terminology cause false conclusions: Vitamin D does not increase the risk of dementia.

Reinhold Vieth

Open access · goldAbstract read
In one paragraph

Article in Aging cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Crosstalk between bone and brain in Alzheimer's disease: Mechanisms, applications, and perspectives.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Reinhold ViethDepartment of Laboratory Medicine and Pathobiology, Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-7489-7816
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been a progressive trend in recent years, to trivialize the terminology surrounding the molecules based on a secosteroid structure. The generic use of the term, "vitamin D," results in gross misrepresentations that confuse the use of a drug commonly used for patients with kidney failure, with the nutritional use of vitamin D. This commentary is a critique of one particularly bad example of that terminological trivialization. Authors may simply want to add impact to their findings when they refer to "vitamin D supplementation" when what they are reporting on is calcitriol. However, the consequences of this practice are to mislead all readers who do not go through the primary publication very carefully to understand the details behind sloppy terminology. Contrary to all the words written in the publication commented upon here, it offers no clinical evidence that vitamin D supplementation increases risk of Alzheimer's disease or dementia.

Indexed as

Alzheimer DiseaseVitamin D DeficiencyCalcitriolHumansVitamin DVitaminsCalcitriolVitamin DVitamins1,25-dihydroxy25-hydroxyvitamin DAlzheimer's diseasecalcidiolcalcitriolcognitiondementiaepidemiologyhormonekidney diseasenutritionvitamin D

Identifiers

PMID36173739
PMCPMC9577943
OpenAlexW4297965113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.