Evidence map›Paper›PMID 36173625›Full record

ArticleAging2022

Identification and validation of prognostic autophagy-related genes associated with immune microenvironment in human gastric cancer.

Ruyue Tian, Ya Sun, Xuedi Han, Jiajun Wang, Hongli Gu, Wenhai Wang, Lei Liang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Investigation of the Mechanism ofInternational journal of general medicine · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ruyue TianDepartment of Ultrasound, Aero Space Central Hospital, Beijing 100050, China.
Ya SunDepartment of Ultrasound, Aero Space Central Hospital, Beijing 100050, China.
Xuedi HanDepartment of Ultrasound, Aero Space Central Hospital, Beijing 100050, China.
Jiajun WangDepartment of Ultrasound, Aero Space Central Hospital, Beijing 100050, China.
Hongli GuDepartment of Ultrasound, Aero Space Central Hospital, Beijing 100050, China.
Wenhai WangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing 100050, China.
Lei LiangDepartment of Ultrasound, Aero Space Central Hospital, Beijing 100050, China.
Aerospace Center Hospital · CNBeijing Friendship Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy-related genes (ATGs) play critical roles in tumorigenesis and progression in gastric cancer (GC). The present study aimed to identify immune-based prognostic ATGs and verify their functions in tumor immune microenvironment (TIME) in GC. Macrophage infiltration was found to negatively correlate with prognosis in GC patients. After stratifying by infiltration levels of macrophages, we screened The Cancer Genome Atlas and Human Autophagy Database to identify the differentially expressed ATGs (DE-ATGs). Of 1,433 differentially expressed genes between the two groups, seven genes qualified as DE-ATGs. Of these,

Indexed as

Stomach NeoplasmsAutophagyGTPase-Activating ProteinsHumansKaplan-Meier EstimatePrognosisTumor MicroenvironmentTumor Suppressor ProteinsDLC1 protein, humanGTPase-Activating ProteinsTumor Suppressor Proteinsautophagy-related genescancer immunitygastric cancerprognosisThe Cancer Genome Atlas

Identifiers

PMID36173625
PMCPMC9550254
OpenAlexW4297519335

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.