Evidence map›Paper›PMID 36173514›Full record

ArticleActa neurochirurgica2022

Mortality after chronic subdural hematoma is associated with frailty.

Jurre Blaauw, Bram Jacobs, Heleen M den Hertog, Niels A van der Gaag, Korné Jellema, Ruben Dammers, Kuan H Kho, Rob J M Groen, Joukje van der Naalt, Hester F Lingsma

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jurre BlaauwDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. j.blaauw02@umcg.nl.ORCID http://orcid.org/0000-0001-8399-2890
Bram JacobsDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Heleen M den HertogDepartment of Neurology, Isala Hospital Zwolle, Zwolle, The Netherlands.
Niels A van der GaagUniversity Neurosurgical Center Holland (UNCH), Leiden University Medical Center, Haaglanden Medical Center & Haga Teaching Hospital, Leiden & The Hague, The Netherlands.
Korné JellemaDepartment of Neurology, Haaglanden Medical Centre, The Hague, The Netherlands.
Ruben DammersDepartment of Neurosurgery, Erasmus MC Stroke Center, Erasmus Medical Center, Rotterdam, The Netherlands.
Kuan H KhoDepartment of Neurosurgery, Medisch Spectrum Twente, Enschede, The Netherlands.
Rob J M GroenDepartment of Neurosurgery, University Medical Center Groningen, Groningen, The Netherlands.
Joukje van der NaaltDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Hester F LingsmaCenter for Medical Decision Sciences, Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic subdural hematoma (CSDH) is a common neurological disease often affecting the elderly. Long-term excess mortality for patients after CSDH has been suggested but causes of death are unknown. We hypothesize that excess mortality of CSDH patients is related to frailty. In this article, we describe mortality rates and causes of death of CSDH patients compared with the general population and assess the association of frailty with mortality.

methodsA cohort study in which consecutive CSDH patients were compared to the general population regarding mortality rates. Furthermore, the association of six frailty indicators (cognitive problems, frequent falling, unable to live independently, unable to perform daily self-care, use of benzodiazepines or psychotropic drugs, and number of medications) with mortality was assessed.

resultsA total of 1307 CSDH patients were included, with a mean age of 73.7 (SD ± 11.4) years and 958 (73%) were male. Median follow-up was 56 months (range: 0-213). Compared with controls CSDH patients had a hazard ratio for mortality of 1.34 (95% CI: 1.2-1.5). CSDH patients more often died from cardiovascular diseases (37% vs. 30%) and falls (7.2% vs. 3.7%). Among CSDH patients frequent falling (HR 1.3; 95% CI: 1.0-1.7), inability to live independently (HR 1.4, 95% CI: 1.1-1.8), inability to perform daily self-care (HR 1.5; 95% CI: 1.1-1.9), and number of medications used (HR 1.0; 95% CI: 1.0-1.1) were independently associated with mortality.

conclusionsCSDH patients have higher mortality rates than the general population. Frailty in CSDH patients is associated with higher mortality risk. More attention for the frailty of CSDH patients is warranted.

Indexed as

FrailtyHematoma, Subdural, ChronicAgedCohort StudiesFemaleHumansMaleProportional Hazards ModelsRetrospective StudiesChronic Subdural hematomaFrailtyMortalitySurvival

Identifiers

PMID36173514
PMCPMC9705486

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.