Evidence map›Paper›PMID 36173486›Full record

ArticleArchives of microbiology2022

Larvicidal, antioxidant and biotoxicity assessment of (2-(((2-ethyl-2 methylhexyl)oxy)carbonyl)benzoic acid isolated from Bacillus pumilus against Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus.

Krishnan Raguvaran, Manickam Kalpana, Thulasiraman Manimegalai, Suresh Kalaivani, Palanisamy Devapriya, Nagarajan Siddharthan, Rengasamy Balakrishnan, Tamil Selvan Silambarasan, Rajan Maheswaran

Abstract read
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In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Metabolites from thePharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Krishnan RaguvaranEntomology Laboratory, Department of Zoology, Periyar University, Tamil Nadu, Salem, 636 011, India.
Manickam KalpanaEntomology Laboratory, Department of Zoology, Periyar University, Tamil Nadu, Salem, 636 011, India.
Thulasiraman ManimegalaiEntomology Laboratory, Department of Zoology, Periyar University, Tamil Nadu, Salem, 636 011, India.
Suresh KalaivaniEntomology Laboratory, Department of Zoology, Periyar University, Tamil Nadu, Salem, 636 011, India.
Palanisamy DevapriyaEntomology Laboratory, Department of Zoology, Periyar University, Tamil Nadu, Salem, 636 011, India.
Nagarajan SiddharthanDepartment of Microbiology, Periyar University, Tamil Nadu, Salem, 636 011, India.
Rengasamy BalakrishnanDepartment of Applied Life Sciences and Integrated Bioscience, Graduate School, Konkuk University, Chungju, 27478, Republic of Korea.
Tamil Selvan SilambarasanDepartment of Microbiology, School of Allied Health Sciences, Vinayaka Missions Research Foundation (DU), Tamil Nadu, Salem, 636 302, India.
Rajan MaheswaranEntomology Laboratory, Department of Zoology, Periyar University, Tamil Nadu, Salem, 636 011, India. mahes1380@gmail.com.
Periyar University · INKonkuk University · KRVinayaka Missions University · IN

Funding

Science and Engineering Research Board DST-SERB-EEQ/2018/000557
6 · The paper itself

Abstract

Mosquitoes are a vector for many dreadful diseases known for their public health concern. The continued use of synthetic insecticides against vector control has led to serious environmental impacts, human health problems, and the development of insect resistance. Hence, alternative mosquito control methods are needed to protect the environment and human health. In the present study, the bioefficacy of (2-(((2-ethyl-2 methylhexyl)oxy)carbonyl) benzoic acid isolated from Bacillus pumilus were tested against Aedes aegypti, Culex quinquefasciatus and Anopheles stephensi. The isolated bioactive compound was characterized through thin layer chromatography (TLC), UV-visible spectroscopy (UV), Fourier-transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and gas chromatography-mass spectrometry analysis. The pure compound caused a high percent mortality rate in a dose-dependent manner, the obtained values were 96, 82, 69, 50 and 34%; 86, 72, 56, 43, and 44%; 100, 90, 83, 70 and 56% against Ae. aegypti, Cx. quinquefasciatus, and An. stephensi respectively. The effective lethal concentration values (LC

Indexed as

AedesAnophelesBacillus pumilusCulexInsecticidesAnimalsAntioxidantsBenzoic AcidCatalaseEsterasesGlutathioneHumansLarvaMosquito VectorsPlant ExtractsPlant LeavesAntioxidantsBenzoic AcidCatalaseEsterasesGlutathioneInsecticidesPlant ExtractsSuperoxide DismutaseTransferases(2-(((2-Ethyl-2 methylhexyl)oxy)carbonyl)benzoic acid)Antioxidant enzymesBacillus pumilusComet assayMosquito larvicidal activityNon-targeted organism

Identifiers

PMID36173486
OpenAlexW4298002047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.