Evidence map›Paper›PMID 36173405›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

Enuresis and upper airway obstruction: BNP and ADH hormones behavior before and after airway surgery.

André Ribeiro, José Murillo Bastos, André Avarese de Figueiredo, Tarssius Capelo Cândido, Wilson Benini Guércio, Bruno O Zica

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PubMed Full text at PMC Publisher
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Primary monosymptomatic nocturnal enuresis highlighted in this number of International Brazilian Journal of Urology.International braz j urol : official journal of the Brazilian Society of Urology
    Article
  4. Weak clinical effect of airway clearance on ADH and BNP concentration: mechanism or data collection BIAS.International braz j urol : official journal of the Brazilian Society of Urology
    Article
  5. Treating asthma in patients with enuresis: repercussions on urinary symptoms.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

André RibeiroDivisão de Otorrinolaringologia, Departamento de Cirurgia, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brasil.
José Murillo BastosDivisão de Urologia, Departamento de Cirurgia, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brasil.
André Avarese de FigueiredoDivisão de Urologia, Departamento de Cirurgia, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brasil.
Tarssius Capelo CândidoDivisão de Otorrinolaringologia, Departamento de Cirurgia, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brasil.
Wilson Benini GuércioDivisão de Otorrinolaringologia, Departamento de Cirurgia, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brasil.
Bruno O ZicaDivisão de Urologia, Departamento de Cirurgia, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brasil.
Universidade Federal de Juiz de Fora · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUpper airway obstruction (UAO) is a common condition in all pediatric population, with a 27% prevalence. Primary monosymptomatic nocturnal enuresis (PMNE) is a condition related to UAO in 8% to 47% of these children. The specific pathophysiological mechanism of this bond is not well understood. Some authors suggest a connection between brain natrituretic peptide (BNP) and anti-diuretic hormone (ADH) during sleep. The aim of this study was to evaluate hormone profile (ADH and BNP) and improvement in dry nights in a sample of children before and after surgical treatment of the UAO.

methodsThis is a longitudinal prospective interventionist study in children, 5 to 14 years of age, with UAO and PMNE recruited in a specialty outpatient clinic. Children presenting UAO and PMNE were evaluated with a 30-day dry night diary and blood samples were collected to evaluate ADH and BNP before and after upper airway surgery. Data were analyzed prior to surgery and 90-120 days after surgery.

resultsTwenty-one children with a mean age of 9.7 years were included. Mean BNP before surgery was 116.5 ± 126.5 pg/mL and 156.2 ± 112.3 pg/mL after surgery (p<0.01). Mean ADH was 5.8 ± 3.2 pg/mL and 14.6 ± 35.4 before and after surgery, respectively (p=0.26). The percentage of dry nights went from 32.3 ± 24.7 before surgery to 75.4 ± 33.4 after surgery (p˂0.01).

conclusionSurgery for airway obstruction contributed to an increase in BNP without increasing ADH. A total of 85.8% of the children presented partial or complete improvement of their enuresis.

Indexed as

Airway ObstructionEnuresisNocturnal EnuresisUrinary IncontinenceChildDiureticsHormonesHumansPeptidesProspective StudiesVasopressinsDiureticsHormonesPeptidesVasopressinsNatriuretic Peptide, BrainNocturnal EnuresisUrination Disorders

Identifiers

PMID36173405
PMCPMC9747030
OpenAlexW4298088570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.