Evidence map›Paper›PMID 36173325›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography.

Snapper R M Magor-Elliott, Asma Alamoudi, Rebecca R Chamley, Haopeng Xu, Tishan Wellalagodage, Rory P McDonald, David O'Brien, Jonathan Collins, Ben Coombs, James Winchester and 16 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Increased intrapulmonary shunt and alveolar dead space post-COVID-19.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
  6. Computed cardiopulmonography and the idealized lung clearance index, iLCIJournal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 1 country.

Snapper R M Magor-ElliottDepartment of Physiology, Anatomy and Genetics, https://ror.org/052gg0110University of Oxford, Oxford, United Kingdom.
Asma AlamoudiDepartment of Physiology, Anatomy and Genetics, https://ror.org/052gg0110University of Oxford, Oxford, United Kingdom.
Rebecca R ChamleyOxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8160-7151
Haopeng XuNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-0245-0844
Tishan WellalagodageDepartment of Physiology, Anatomy and Genetics, https://ror.org/052gg0110University of Oxford, Oxford, United Kingdom.
Rory P McDonaldRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
David O'BrienRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
Jonathan CollinsRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
Ben CoombsRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
James WinchesterRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
Ed SellonRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
Cheng XieOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Dominic SandhuDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Christopher J FullertonDepartment of Physiology, Anatomy and Genetics, https://ror.org/052gg0110University of Oxford, Oxford, United Kingdom.
John H CouperDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Nicholas M J SmithDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Graham RichmondDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Mark P CassarDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Betty RamanOxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom.
Nick P TalbotDepartment of Physiology, Anatomy and Genetics, https://ror.org/052gg0110University of Oxford, Oxford, United Kingdom.
Alexander N BennettAcademic Department of Medical Rehabilitation, Stanford Hall, Loughborough, United Kingdom.
Edward D NicolRoyal Centre for Defence Medicine, Birmingham, United Kingdom.
Grant A D RitchieDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Nayia PetousiNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
David A HoldsworthRoyal Centre for Defence Medicine, Birmingham, United Kingdom.ORCID 0000-0003-2465-1521
Peter A RobbinsDepartment of Physiology, Anatomy and Genetics, https://ror.org/052gg0110University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-4975-0609
University of Oxford · GBRoyal Navy · GBLoughborough College · GBOxford University Hospitals NHS Trust · GB

Funding

British Heart Foundation (BHF)| Clarendon FundDefence Medical Services GroupNational Institute for Health Research (NHIR)NIHR | NIHR Oxford Biomedical Research Centre (OxBRC)NIHR research capability fund (RCF)Oxford British Heart Foundation Centre for Research Excellence RE/18/3/34214Saudi Arabia GovernmentUniversity of Oxford COVID-19 Research Response Fun
6 · The paper itself

Abstract

The longer-term effects of COVID-19 on lung physiology remain poorly understood. Here, a new technique, computed cardiopulmonography (CCP), was used to study two COVID-19 cohorts (MCOVID and C-MORE-LP) at both ∼6 and ∼12 mo after infection. CCP is comprised of two components. The first is collection of highly precise, highly time-resolved measurements of gas exchange with a purpose-built molecular flow sensor based around laser absorption spectroscopy. The second component is estimation of physiological parameters by fitting a cardiopulmonary model to the data set. The measurement protocol involved 7 min of breathing air followed by 5 min of breathing pure O

Indexed as

COVID-19HumansLungRespirationRespiration, ArtificialRespiratory Function TestsCOVID-19humanlaser absorption spectroscopylung volumesrespiratory dead space

Identifiers

PMID36173325
PMCPMC9639770
OpenAlexW4297964477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.