Evidence map›Paper›PMID 36173297›Full record

ArticleMicrobiology spectrum2022

Preferential Selection of Low-Frequency, Lipopolysaccharide-Modified, Colistin-Resistant Mutants with a Combination of Antimicrobials in Acinetobacter baumannii.

Go Kamoshida, Noriteru Yamada, Tomoka Nakamura, Daiki Yamaguchi, Daichi Kai, Maho Yamashita, Chiaki Hayashi, Nana Kanda, Moe Sakaguchi, Hitoshi Morimoto and 5 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  3. Article
  4. Colistin: Lights and Shadows of an Older Antibiotic.Molecules (Basel, Switzerland) · 2024
    Review
  5. Article
  6. PmrAB, the two-component system ofJournal of bacteriology · 2024
    Article
  7. Treatment Strategies of Colistin ResistanceAntibiotics (Basel, Switzerland) · 2024
    Review
  8. Frontiers in microbiology · 2024
    Review
  9. Colistin Resistance inAntibiotics (Basel, Switzerland) · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Go KamoshidaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.ORCID 0000-0001-6300-0911
Noriteru YamadaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Tomoka NakamuraDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Daiki YamaguchiDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Daichi KaiDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Maho YamashitaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Chiaki HayashiDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Nana KandaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Moe SakaguchiDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Hitoshi MorimotoDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Teppei SawadaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Tomoko OkadaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Yuki KayaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Norihiko TakemotoPathogenic Microbe Laboratory, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Kinnosuke YahiroDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical Universitygrid.411212.5, Kyoto, Japan.
Kyoto Pharmaceutical University · JPNational Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin, which targets lipopolysaccharide (LPS), is used as a last-resort drug against severe infections caused by drug-resistant Acinetobacter baumannii. However, A. baumannii possesses two colistin-resistance mechanisms. LPS modification caused by mutations in

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsDisinfectantsAnti-Bacterial AgentsCarbapenemsCiprofloxacinColistinDrug Resistance, Multiple, BacterialHumansLipopolysaccharidesMeropenemMicrobial Sensitivity TestsAnti-Bacterial AgentsCarbapenemsCiprofloxacinColistinDisinfectantsLipopolysaccharidesMeropenemAcinetobacter baumanniicolistinLPSlpxACDmeropenempmrAB

Identifiers

PMID36173297
PMCPMC9602988
OpenAlexW4297964845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.