Evidence map›Paper›PMID 36173294›Full record

ArticleMicrobiology spectrum2022

Differentiation of Classical Swine Fever Virus Virulent and Vaccine Strains by CRISPR/Cas13a.

Yuhang Zhang, Qingmei Li, Ruining Wang, Li Wang, Xun Wang, Jun Luo, Guangxu Xing, Guanmin Zheng, Bo Wan, Junqing Guo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. High-Performance Detection ofFoods (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yuhang ZhangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural Universitygrid.108266.b, Zhengzhou, China.
Qingmei LiKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Ruining WangHenan University of Animal Husbandry and Economy, College of Veterinary Medicine, Zhengzhou, China.
Li WangKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Xun WangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural Universitygrid.108266.b, Zhengzhou, China.
Jun LuoKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Guangxu XingKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Guanmin ZhengPublic Health and Preventive Medicine Teaching and Research Center, Henan University of Chinese Medicine, Zhengzhou, China.
Bo WanInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural Universitygrid.108266.b, Zhengzhou, China.
Junqing GuoKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Gaiping ZhangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural Universitygrid.108266.b, Zhengzhou, China.ORCID 0000-0002-3834-9975
Henan Academy of Agricultural Sciences · CNHenan Agricultural University · CNFirst Affiliated Hospital of Henan University · CNHenan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a notifiable terrestrial and aquatic animal disease listed by World Organisation for Animal Health (formerly the Office International des Epizooties [OIE]), classical swine fever (CSF) has caused great economic losses to the swine industry worldwide during recent decades. Differentiation of infected and vaccinated animals (DIVA) is urgent for eradication of CSF. In this study, a diagnostic platform based on CRISPR/Cas13a was established with the ability to differentiate between classical swine fever virus (CSFV) virulent and vaccine strains. In combination with reverse transcription recombinase-aided amplification (RT-RAA), the detection limit for CSFV synthetic RNA templates reached 3.0 × 10

Indexed as

African Swine Fever VirusClassical Swine FeverClassical Swine Fever VirusNucleic AcidsViral VaccinesAnimalsClustered Regularly Interspaced Short Palindromic RepeatsRecombinasesRNASensitivity and SpecificitySwineNucleic AcidsRecombinasesRNAViral Vaccinesclassical swine fever virusCRISPR/Cas13adifferentiation of infected and vaccinated animalsrecombinase-aided amplification

Identifiers

PMID36173294
PMCPMC9603908
OpenAlexW4297965478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.