Evidence map›Paper›PMID 36172996›Full record

ArticleThe Journal of international medical research2022

Comparison of perinephric fat measurements between malignant and benign renal tumours.

Jui-Peng Tsai, Dao-Chen Lin, Wei-Ming Huang, Marcelo Chen, Yi-Hsuan Chen

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Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jui-Peng TsaiDivision of Cardiology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei.
Dao-Chen LinDepartment of Radiology, Taipei Veterans General Hospital, Taipei.
Wei-Ming HuangDepartment of Radiology, Mackay Memorial Hospital, Taipei.
Marcelo ChenDepartment of Medicine, Mackay Medical College, New Taipei City.
Yi-Hsuan ChenDepartment of Urology, Mackay Memorial Hospital, Taipei.ORCID 0000-0002-4362-7001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate different parameters derived from the quantity and quality of perinephric fat, and to compare their effectiveness in predicting the malignant pathology of renal tumours.

methodsData from patients diagnosed with renal tumour between April 2014 and December 2020 were retrospectively reviewed, and patients were categorized into malignant or benign tumour groups. Fat parameters, including perinephric fat volume (PFV), perinephric fat area (PFA), perinephric fat thickness (PFT), and Mayo adhesive probability (MAP) score were measured using abdominal computed tomography scans. Between-group differences were assessed by analysis of variance and χ

resultsA total of 109 patients were included. MAP score, PFV, PFA, and PFT were significantly increased in the malignant versus benign tumour group, and after correction for body mass index (BMI), the indexed PFV/BMI, PFA/BMI, and PFT/BMI values remained significantly higher in the malignant tumour group. All parameters showed fair predictivity of malignancy, with comparable area under the curve values in the ROC curve.

conclusionAn increased amount of perinephric fat is predictive of malignant pathology for renal tumours. The predictive accuracy for each perinephric fat parameter remained fair after correcting for BMI.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsAdipose TissueHumansKidneyNephrectomyRetrospective Studiesbody mass indexcomputed tomographyMayo adhesive probabilityperinephric fatprediction of malignancyRenal tumour

Identifiers

PMID36172996
PMCPMC9528033

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