ArticleEuropean heart journal2022
Plaque histology and myocardial disease in sudden coronary death: the Fingesture study.
Article in European heart journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 57 citations in OpenAlex.
- Intravascular imaging in myocardial infarction and ischemia with nonobstructive coronary arteries.Cardiovascular intervention and therapeutics · 2026Review
- Myocardial fibrosis in patients with coronary artery disease and diabetes mellitus assessed by cardiovascular magnetic resonance T1 mapping.The international journal of cardiovascular imaging · 2026Article
- Incremental prognostic value of CCTA-based myocardial radiomics over clinical factors, anatomic and hemodynamic CTA findings in patients with stable angina.The international journal of cardiovascular imaging · 2026Review
- Anomalous Coronary Artery Origin from Pulmonary Artery and Coronary Fistulas: A Review About Coronary Steal Phenomenon.Children (Basel, Switzerland) · 2026Review
- Left ventricular ejection fraction and myocardial fibrosis in sudden cardiac death.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Insights into Pre-COVID sudden cardiac deaths-: An autopsy study in South India.Journal of family medicine and primary care · 2025Article
- Current causes of sudden death in large populations: differences between resuscitated patients and autopsied cases.European heart journal open · 2025Article
- Sudden Cardiac Arrest in a Young Male: The Role of Intraplaque Hemorrhage and Coronary Spasm.JACC. Case reports · 2025Article
- Investigation of Myocardial Substrate for Sudden Arrhythmic Death in Coronary Artery Disease Without Acute Coronary Thrombosis or Myocardial Infarction.Journal of the American Heart Association · 2025Article
- Novel insights into myocardial fibrosis in patients with new onset ST-elevation myocardial infarction following percutaneous coronary intervention through enhanced cardiac magnetic resonance imaging: a prospective cohort study.BMC cardiovascular disorders · 2025Article
- Intraplaque Hemorrhage Is a Key Finding in Sudden Cardiac Death Resulting From Coronary Vasospasm.JACC. Case reports · 2025Article
- Predictive Effect of Atypical Right Bundle-Branch Block on In-Hospital Sudden Cardiac Death and Cardiac Rupture and Long-Term Prognosis in Patients With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention.Journal of the American Heart Association · 2025Article
- Sudden cardiac death and its histopathological findings in autopsy cases in Jharkhand.Journal of family medicine and primary care · 2025Article
- Right Bundle Branch Block on ECG as a Predictor of Sudden Cardiac Arrest Due to Pulmonary Embolism.The American journal of case reports · 2025Article
- Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review.Archives of medical science : AMS · 2025Article
- An Easy-to-Use Risk Stratification System for NSTE-ACS Patients Combining Autonomic Nervous System and Coronary Physiology.International journal of medical sciences · 2025Article
- Out of hospital cardiac arrest - new insights and a call for a worldwide registry and guidelines.BMC emergency medicine · 2024Article
- Identification of sudden cardiac death from human blood using ATR-FTIR spectroscopy and machine learning.International journal of legal medicine · 2024Article
- Day-of-the-week variation of sudden unexpected cardiac death.International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Artificial Intelligence Model Predicts Sudden Cardiac Arrest Manifesting With Pulseless Electric Activity Versus Ventricular Fibrillation.Circulation. Arrhythmia and electrophysiology · 2024Article
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsAt least 50% of deaths due to coronary artery disease (CAD) are sudden cardiac deaths (SCDs), but the role of acute plaque complications on the incidence of sudden death in CAD is somewhat unclear. The present study aimed to investigate plaque histology and concomitant myocardial disease in sudden coronary death. METHODS AND
resultsThe study population is derived from the Fingesture study, which has collected data from 5869 consecutive autopsy-verified SCD victims in Northern Finland (population ≈600 000) between 1998 and 2017. In this substudy, histological examination of culprit lesions was performed in 600 SCD victims whose death was due to CAD. Determination of the cause of death was based on the combination of medical records, police reports, and autopsy data. Plaque histology was classified as either (i) plaque rupture or erosion, (ii) intraplaque haemorrhage, or (iii) stable plaque. The mean age of the study subjects was 64.9 ± 11.2 years, and 82% were male. Twenty-four per cent had plaque rupture or plaque erosion, 24% had an intraplaque haemorrhage, and 52% had a stable plaque. Myocardial hypertrophy was present in 78% and myocardial fibrosis in 93% of victims. The presence of myocardial hypertrophy or fibrosis was not associated with specific plaque histology.
conclusionLess than half of sudden deaths due to CAD had evidence of acute plaque complication, an observation which is contrary to historical perceptions. The prevalence of concomitant myocardial disease was high and independent of associated plaque morphology.
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