Evidence map›Paper›PMID 36172466›Full record

ArticleFrontiers in behavioral neuroscience2022

Predictors of prodromal Parkinson's disease in young adult

Sarah A Lechner, Jacob M Welsch, Natalie K Pahapill, Taylor A R Kaldenberg, Amy Regenbaum, Cynthia A Kelm-Nelson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Positron Emission Tomography (PET) Neuroimaging of theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Article
  5. Positron emission tomography neuroimaging of [Frontiers in neuroscience · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sarah A LechnerDepartment of Surgery, Division of Otolaryngology, University of Wisconsin-Madison, Madison, WI, United States.
Jacob M WelschDepartment of Surgery, Division of Otolaryngology, University of Wisconsin-Madison, Madison, WI, United States.
Natalie K PahapillDepartment of Surgery, Division of Otolaryngology, University of Wisconsin-Madison, Madison, WI, United States.
Taylor A R KaldenbergDepartment of Surgery, Division of Otolaryngology, University of Wisconsin-Madison, Madison, WI, United States.
Amy RegenbaumDepartment of Surgery, Division of Otolaryngology, University of Wisconsin-Madison, Madison, WI, United States.
Cynthia A Kelm-NelsonDepartment of Surgery, Division of Otolaryngology, University of Wisconsin-Madison, Madison, WI, United States.
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Pathways, mechanisms, and treatments of vocal communication deficits in a Parkinson rat modelR01NS117469 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Cynthia A Kelm-Nelson · 2020 to 2026
$3.0M
Communication dysfunction in Parkinson disease: Integrated genetic and protein expression analysis of neural pathways to identify treatment targetsR21DC016135 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI KELM-NELSON, CYNTHIA A · 2018 to 2020
$459k
Automated Tissue MicroarrayerS10OD023526 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI MATKOWSKYJ, KRISTINA A. · 2018 to 2018
$184k
NCATS NIH HHS UL1 TR002373NCI NIH HHS P30 CA014520NIDCD NIH HHS R21 DC016135NIH HHS S10 OD023526NINDS NIH HHS R01 NS117469
6 · The paper itself

Abstract

Parkinson's disease (PD) is a progressive, degenerative disease that affects nearly 10 million people worldwide. Hallmark limb motor signs and dopamine depletion have been well studied; however, few studies evaluating early stage, prodromal biology exist.

Indexed as

anxietymotorParkinson’s diseasePINK1ratultrasonic vocalization (USV)

Identifiers

PMID36172466
PMCPMC9510667
OpenAlexW4296524478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.