Evidence map›Paper›PMID 36172431›Full record

ArticleJTCVS open2022

Acute kidney injury following cardiopulmonary bypass in Jamaica.

Lori-Ann Fisher, Sunil Stephenson, Marshall Tulloch Reid, Simon G Anderson

Abstract read
In one paragraph

Article in JTCVS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lori-Ann FisherDepartment of Medicine, The University of the West Indies, Mona, Jamaica.
Sunil StephensonDepartment of Surgery, Radiology, Anaesthesia and Intensive Care, The University of the West Indies, Mona, Jamaica.
Marshall Tulloch ReidCaribbean Institute for Health Research, The University of the West Indies, Mona, Jamaica.
Simon G AndersonCaribbean Institute for Health Research, The University of the West Indies, Mona, Jamaica.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The study objectives were to describe the incidence, risk factors, and outcomes of acute kidney injury after cardiopulmonary bypass in Jamaica. Method: We performed a review of the medical records of adult patients (aged ≥ 18 years) with no prior dialysis requirement undergoing cardiopulmonary bypass at the University Hospital of the West Indies, Mona, between January 1, 2016, and June 30, 2019. Demographic, preoperative, intraoperative, and postoperative data were abstracted. Acute kidney injury was defined using Kidney Disease Improving Global Outcomes criteria. The primary outcomes were acute kidney injury incidence and all-cause 30-day mortality. Multivariable logistic regression and Cox proportional analyses were used to examine the association between the acute kidney injury risk factors and the primary outcome. Results: Data for 210 patients (58% men, mean age 58.1 ± 12.9 years) were analyzed. Acute kidney injury occurred in 80 patients (38.1%), 44% with Kidney Disease Improving Global Outcomes I, 33% with Kidney Disease Improving Global Outcomes II, and 24% with Kidney Disease Improving Global Outcomes III. From multivariable logistic regression models, European System for Cardiac Operative Risk Evaluation II (odds ratio, 1.19; 95% confidence interval, 1.01-1.39 per unit), bypass time (odds ratio, 1.94; 95% confidence interval, 1.40-2.67 per hour), perioperative red cell transfusion (odds ratio, 3.03; 95% confidence interval, 1.36-6.76), and postoperative neutrophil lymphocyte ratio (odds ratio, 1.65; 95% confidence interval, 1.01-2.68 per 10-unit difference) were positively associated with acute kidney injury. Acute kidney injury resulted in greater median hospital stay (18 vs 11 days, Conclusions: Acute kidney injury after cardiopulmonary bypass surgery occurs frequently in Jamaica and results in poor short-term outcomes. Further studies coupled with quality interventions to reduce the mortality of those with acute kidney injury are needed in the Caribbean.

Indexed as

acute kidney injuryAKI, acute kidney injuryBMI, body mass indexCABG, coronary artery bypass graftingcardiopulmonary bypassCaribbeanCI, confidence intervalCKD, chronic kidney diseaseeGFR, estimated glomerular filtration rateeuroSCORE, European System for Cardiac Operative Risk EvaluationeuroSCORE IIHR, hazard ratioICU, intensive care unitIQR, interquartile rangeKDIGO, Kidney Disease Improving Global Outcomesneutrophil lymphocyte ratioNLR, neutrophil lymphocyte ratioOR, odds ratioRBC, red blood cellSCr, serum creatinine

Identifiers

PMID36172431
PMCPMC9510884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.