Evidence map›Paper›PMID 36172405›Full record

ArticleJTCVS open2022

Influence of center surgical aortic valve volume on outcomes of transcatheter aortic valve replacement.

Matthew Gandjian, Arjun Verma, Zachary Tran, Yas Sanaiha, Peter Downey, Richard J Shemin, Peyman Benharash

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JTCVS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Racial disparities in transcatheter aortic valve replacement: A contemporary nationwide analysis.American heart journal plus : cardiology research and practice · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthew GandjianCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.
Arjun VermaCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.
Zachary TranCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.
Yas SanaihaCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.
Peter DowneyCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.
Richard J SheminCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.
Peyman BenharashCardiovascular Outcomes Research Laboratory, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, Calif.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The utilization of transcatheter aortic valve replacement (TAVR) technology has exceeded that of traditional surgical aortic valve replacement (SAVR). In addition, the role of minimum surgical volume requirements for TAVR centers has recently been disputed. The present work evaluated the association of annual institutional SAVR caseload on outcomes following TAVR. Methods: The 2012-2018 Nationwide Readmissions Database was queried for elective TAVR hospitalizations. The study cohort was split into early (Era 1: 2012-2015) and late (Era 2: 2016-2018) groups. Based on restricted cubic spline modeling of annual hospital SAVR caseload, institutions were dichotomized into low-volume and high-volume centers. Multivariable regressions were used to determine the influence of high-volume status on in-hospital mortality and perioperative complications following TAVR. Results: An estimated 181,740 patients underwent TAVR from 2012 to 2018. Nationwide TAVR volume increased from 5893 in 2012 to 49,983 in 2018. After adjustment for relevant patient and hospital factors, high-volume status did not alter odds of TAVR mortality in Era 1 (adjusted odds ratio, 0.94; Conclusions: SAVR experience is associated with improved TAVR outcomes in a modern cohort. Our findings suggest the need for continued collaboration between cardiologists and surgeons to maximize patient safety.

Indexed as

AKI, acute kidney injuryaortic valve replacementcardiac surgeryclinical outcomesCVA, cerebrovascular accidentECI, Elixhauser Comorbidity IndexHVH, high-volume hospitalICD-9/10, International Classification of Diseases 9th and 10th revisionsLASSO, least absolute shrinkage and selection operatorLOS, length of stayLVH, low-volume hospitalMI, myocardial infarctionNCD, National Coverage DeterminationNPtrend, nonparametric test of trendsNRD, Nationwide Readmissions DatabaseSAVR, surgical aortic valve replacementTAVR, transcatheter aortic valve replacementtranscatheter aortic valve replacement

Identifiers

PMID36172405
PMCPMC9510825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.