Evidence map›Paper›PMID 36172363›Full record

ArticleFrontiers in immunology2022

T cell interaction with activated endothelial cells primes for tissue-residency.

Judith Wienke, Saskia R Veldkamp, Eva M Struijf, Fjodor A Yousef Yengej, M Marlot van der Wal, Annet van Royen-Kerkhof, Femke van Wijk

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. CD8Nature reviews. Cardiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Interplay Between Immunity, Inflammation and Endothelial Dysfunction.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Judith WienkeCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
Saskia R VeldkampCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
Eva M StruijfCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
Fjodor A Yousef YengejCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
M Marlot van der WalCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
Annet van Royen-KerkhofPediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, Netherlands.
Femke van WijkCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
University Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue-resident memory T cells (TRM) are suspected drivers of chronic inflammation, but their induction remains unclear. Since endothelial cells (EC) are obligate interaction partners for T cells trafficking into inflamed tissues, they may play a role in TRM development. Here, we used an

Indexed as

Immunologic MemoryCD8-Positive T-LymphocytesCell CommunicationCytokinesEndothelial CellsHumansIntegrin alpha1Intercellular Adhesion Molecule-1Interleukin-15Ki-67 AntigenProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-CellTranscription FactorsVascular Cell Adhesion Molecule-1CytokinesIntegrin alpha1Intercellular Adhesion Molecule-1Interleukin-15Ki-67 AntigenProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-CellTranscription FactorsVascular Cell Adhesion Molecule-1CD69endothelial cellinflammationT cell differentiationtissue-resident memory T cells

Identifiers

PMID36172363
PMCPMC9510578
OpenAlexW4296527506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.