Evidence map›Paper›PMID 36172285›Full record

ArticleFrontiers in cell and developmental biology2022

Nodal asymmetry and hedgehog signaling during vertebrate left-right symmetry breaking.

Maria Isabella Negretti, Nina Böse, Natalia Petri, Stanislav Kremnyov, Nikoloz Tsikolia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Molecular anatomy of emerging Xenopus left-right organizer at successive developmental stages.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  3. Left-right symmetry breaking: learning from the chicken.Frontiers in cell and developmental biology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Maria Isabella NegrettiAnatomy and Embryology, University Medical Center Göttingen, Göttingen, Germany.
Nina BöseAnatomy and Embryology, University Medical Center Göttingen, Göttingen, Germany.
Natalia PetriDepartment of Embryology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Stanislav KremnyovDepartment of Embryology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Nikoloz TsikoliaAnatomy and Embryology, University Medical Center Göttingen, Göttingen, Germany.
Universitätsmedizin Göttingen · DELomonosov Moscow State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of visceral left-right asymmetry in bilateria is based on initial symmetry breaking followed by subsequent asymmetric molecular patterning. An important step is the left-sided expression of transcription factor

Indexed as

chick embryoembryonic competenceheart loopinghedgehog signalingleft–right (LR) asymmetrynodalXenopus laevis embryo

Identifiers

PMID36172285
PMCPMC9511907
OpenAlexW4295886456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.