Evidence map›Paper›PMID 36172263›Full record

ArticleFrontiers in molecular neuroscience2022

The feedback loop between calcineurin, calmodulin-dependent protein kinase II, and nuclear factor of activated T-cells regulates the number of GABAergic neurons during planarian head regeneration.

Hui Zhen, Mingyue Zheng, Huazhi Geng, Qian Song, Lili Gao, Zuoqing Yuan, Hongkuan Deng, Qiuxiang Pang, Bosheng Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hui ZhenLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Mingyue ZhengGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Huazhi GengZibo Maternal and Child Health Hospital, Zibo, China.
Qian SongLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Lili GaoLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Zuoqing YuanLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Hongkuan DengLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Qiuxiang PangLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Bosheng ZhaoLaboratory of Developmental and Evolutionary Biology, Shandong University of Technology, Nantong, China.
Shandong University of Technology · CNGuangdong Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disturbances in the excitatory/inhibitory balance of brain neural circuits are the main source of encephalopathy during neurodevelopment. Changes in the function of neural circuits can lead to depolarization or repeat rhythmic firing of neurons in a manner similar to epilepsy. GABAergic neurons are inhibitory neurons found in all the main domains of the CNS. Previous studies suggested that

Indexed as

CalnCamkIIGABAergic neuronsNFATplanarianregeneration

Identifiers

PMID36172263
PMCPMC9510629
OpenAlexW4296523942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.