Evidence map›Paper›PMID 36171930›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

Widening spectrum of neuroleptic malignant syndrome: Case series.

Gunchan Paul, Sachi Singhal, Birinder S Paul, Gurparvesh Singh, Shriya Goyal

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Gunchan PaulDepartment of Critical Care Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Sachi SinghalMMBS MD, Crozer Chester Medical Center, Upland PA, US.
Birinder S PaulDepartment of Neurology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Gurparvesh SinghDepartment of Neurology, MBBS Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Shriya GoyalDepartment of Neurology, MBBS Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Crozer-Keystone Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroleptic malignant syndrome (NMS) is a rare and rapidly progressive syndrome with mortality rate of 5.6%. The spectrum of onset, progression and outcome is heterogeneous and is associated with number of risk factors. In our case series, we entail the triggers, hospital course and outcome of five interesting in-patient cases that were admitted to our service in a tertiary care hospital in Northern India. This case series is to highlight the first ever reported case of NMS triggered by levosulpiride administration, along with one of the few first cases of NMS after programming of DBS, hypothyroid disorders, levodopa readjustment and selective basal ganglia and cerebellar injury following the hyperthermic syndrome. This is also to bring to attention of clinicians worldwide the atypical risk factors of NMS, and stress the importance of staying vigilant for the same by frequent follow-ups and high degree of clinical suspicion. We also aim to generate epidemiological data about these atypical triggers.

Indexed as

NMS is a rare condition with mortality rate and requires early identification of the syndrome with high clinical suspicion. We hereby report five different triggers for hypo-dopaminergic state leading to NMS to sensitize the physicians regarding the atypical risk factors

Identifiers

PMID36171930
PMCPMC9511852
OpenAlexW4288063872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.