Evidence map›Paper›PMID 36171817›Full record

ArticleFrontiers in surgery2022

No obvious advantage of hyperthermic intraperitoneal chemotherapy after interval debulking surgery in the treatment of advanced ovarian cancer: A retrospective study.

Mengmeng Lyu, Jin Lu, Yang Shen, Qianqian Chen, Fei Deng, Jinhua Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mengmeng LyuDepartment of Gynecologic Oncology, Jiangsu Cancer Hospital / Jiangsu Institute of Cancer Research / The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Jin LuDepartment of Gynecologic Oncology, Jiangsu Cancer Hospital / Jiangsu Institute of Cancer Research / The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Yang ShenDepartment of Gynecologic Oncology, Jiangsu Cancer Hospital / Jiangsu Institute of Cancer Research / The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Qianqian ChenDepartment of Gynecologic Oncology, Jiangsu Cancer Hospital / Jiangsu Institute of Cancer Research / The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Fei DengDepartment of Gynecologic Oncology, Jiangsu Cancer Hospital / Jiangsu Institute of Cancer Research / The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Jinhua WangDepartment of Gynecologic Oncology, Jiangsu Cancer Hospital / Jiangsu Institute of Cancer Research / The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Cancer Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study the efficacy of interval debulking surgery (IDS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) compared to IDS alone for the treatment of ovarian cancer after neoadjuvant chemotherapy (NACT). Methods: We conducted a retrospective study of patients with stage IIIC/IV high-grade serous ovarian carcinoma who underwent surgery at our center from January 2018 to December 2019. Patients who underwent IDS after NACT with ( Results: The median progression-free survival (PFS) was 14.05 months in the IDS plus HIPEC group and 12.97 months in the IDS group ( Conclusion: After NACT, IDS plus HIPEC did not show significant PFS and tumor index change ratio benefits over IDS alone in patients with primary ovarian cancer. Further investigations are needed to assess the role of HIPEC in the treatment of ovarian cancer.

Indexed as

HIPECinterval debulkingneoadjuvant chemotherapyovarian cancerretrospective

Identifiers

PMID36171817
PMCPMC9510392
OpenAlexW4296527878

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.