Evidence map›Paper›PMID 36171746›Full record

ReviewFrontiers in microbiology2022

Relationships among microbiota, gastric cancer, and immunotherapy.

Yuzhen Li, Xiaona Huang, Desheng Tong, Chenyu Jiang, Xiaodan Zhu, Zhipeng Wei, Tingjie Gong, Chunhui Jin

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Effect of microbiome group on immune checkpoint inhibitors in treatment of gastrointestinal tumors.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuzhen LiDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Xiaona HuangDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Desheng TongKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.
Chenyu JiangDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Xiaodan ZhuDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Zhipeng WeiDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Tingjie GongDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Chunhui JinDepartment of Oncology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Nanjing University of Chinese Medicine · CNJiangsu Institute of Parasitic Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, conventional neoadjuvant therapy or postoperative adjuvant therapy, such as chemotherapy and radiation therapy, can only bring limited survival benefits to gastric cancer (GC). Median survival after palliative chemotherapy is also low, at about 8-10 months. Immunotargeting is a new option for the treatment of GC, but has not been widely replicated. The highly immunosuppressed tumor microenvironment (TME) discounts the efficacy of immunotherapy for GC. Therefore, new strategies are needed to enhance the immune response of the TME. This paper reviewed the relationship between microorganisms and GC, potential links between microorganisms and immunotherapy and research of microorganisms combined immunotherapy.

Indexed as

CTLA-4gastric cancerimmune checkpoint inhibitorsimmune responsemicrobiotaPD-L1

Identifiers

PMID36171746
PMCPMC9511979
OpenAlexW4295886593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.