Evidence map›Paper›PMID 36171731›Full record

ArticleClinical pediatrics2023

Increase in Rate of Hospitalizations for Pediatric Intentional Acetaminophen Ingestion at a Single Center During the COVID-19 Pandemic.

Rachel E Moss, Emily H Hertzberg, Hannibal Person, Guillaume Stoffels, Sheemon Zackai, John Bucuvalas, Jennifer K Gillen

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Clinical pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rachel E MossDivision of Pediatric Critical Care, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.ORCID 0000-0002-2775-0309
Emily H HertzbergDivision of Pediatric Hospital Medicine, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
Hannibal PersonDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.
Guillaume StoffelsDepartment of Biostatistical Support, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
Sheemon ZackaiDivision of Pediatric Critical Care, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
John BucuvalasDivision of Pediatric Hepatology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
Jennifer K GillenDivision of Pediatric Critical Care, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.ORCID 0000-0003-2905-4822
Icahn School of Medicine at Mount Sinai · USMount Sinai Hospital · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSocial disruption due to COVID-19 has detrimentally affected American adolescents' emotional well-being. Within our system, pediatric acetaminophen ingestions increased in 2020, compared with previous years. We sought to evaluate the rate of hospitalizations for acetaminophen self-harm ingestions and self-harm of adolescents during the COVID-19 pandemic. STUDY

designWe identified patients (aged 0-23) from billing data with diagnosis of acetaminophen ingestion with self-harm intent (ICD-10 code T391X2A), from a multicenter urban, quaternary health care system. We performed retrospective chart review from 2016 to 2020 and performed statistics using a generalized estimating equation (GEE) logistic regression model.

resultsFrom 2016 to 2020, there were 25 790 discharges of adolescents with 65 acetaminophen self-harm ingestion and 148 self-harm discharges. Of the 65 acetaminophen patients, 75% identified as female and 54% identified as non-white; 71% with Medicaid insurance. The proportion of acetaminophen ingestion and self-harm admissions increased from 0.13% in 2016 to 0.46% by 2020 and 0.42% in 2016 to 0.73% by 2020, respectively. The odds of acetaminophen ingestion admission increased by 28% each additional year (odds ratio = 1.28; 95% confidence interval: 1.08, 1.53;

conclusionsAcetaminophen ingestion for self-harm has significantly increased, while overall self-harm has increased to a lesser, nonsignificant degree. Primarily females of color and those with Medicaid insurance are affected. It is important to note this growing, disturbing trend, and to continue to screen for depression in our adolescent community and ensure access to mental health resources.

Indexed as

AcetaminophenCOVID-19AdolescentChildEatingFemaleHospitalizationHumansPandemicsRetrospective StudiesAcetaminophenAcetaminophenCOVID-19ingestionmental health

Identifiers

PMID36171731
PMCPMC10102816
OpenAlexW4297503517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.