Evidence map›Paper›PMID 36171409›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Molecular imaging of fibroblast activity in pressure overload heart failure using [

Guokun Wang, Qinqin Yang, Shengyong Wu, Xudong Xu, Xiao Li, Siyu Liang, Guixia Pan, Changjing Zuo, Xianxian Zhao, Chao Cheng and 1 more

Abstract readComment
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Next-generation molecular imaging of cardiac fibrosis.The international journal of cardiovascular imaging · 2026
    Review
  2. European journal of nuclear medicine and molecular imaging · 2026
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  14. Toward Quantitative Multisite Preclinical Imaging Studies in Acute Myocardial Infarction: Evaluation of the Immune-Fibrosis Axis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Guokun Wang *Department of Cardiovascular Surgery, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, Shanghai, China.
Qinqin Yang *Department of Nuclear Medicine, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Shengyong WuDepartment of Military Health Statistics, Naval Medical University, Shanghai, China.
Xudong XuDepartment of Cardiology, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Xiao LiDepartment of Nuclear Medicine, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Siyu LiangDepartment of Nuclear Medicine, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Guixia PanDepartment of Nuclear Medicine, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Changjing ZuoDepartment of Nuclear Medicine, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Xianxian ZhaoDepartment of Cardiology, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.
Chao Cheng *Department of Nuclear Medicine, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China. 13501925757@163.com.
Suxuan Liu *Department of Cardiology, the First Affiliated Hospital (Changhai Hospital) of Naval Medical University, 168 Changhai Road, Shanghai, 200433, China. suxuan.liu@qq.com.ORCID http://orcid.org/0000-0003-4696-7623
Second Military Medical University · CN

Funding

"234 Discipline Climbing Plan" of the First Affiliated Hospital of Naval Medical University 2019YPT002"234 Discipline Climbing Plan" of the First Affiliated Hospital of Naval Medical University 2020YPT002Shanghai Science and Technology Innovation Action Plan "Science and Technology Support Project in Biomedical Science" 21S11906000
6 · The paper itself

Abstract

purposeWe aimed to evaluate whether [

methodsSprague-Dawley rats underwent abdominal aortic constriction (AAC) (n = 12) and sham surgery (n = 10). All rats were scanned with [

resultsCompared with the sham group, the AAC group presented with decreased ejection fraction (EF) and fractional shortening (FS) and increased left ventricular internal dimensions in diastole (LVIDd) and systole (LVIDs) at 4 and 8 weeks (all p < 0.01). The AAC group showed higher [

conclusionsThe activated fibroblasts in the heart and liver after pressure overload can be monitored by [

Indexed as

Heart FailurePositron Emission Tomography Computed TomographyAnimalsFibroblastsGallium RadioisotopesMolecular ImagingQuinolinesRatsRats, Sprague-Dawley68Ga-FAPIGallium RadioisotopesQuinolinesFAPI-PETFibroblast activation proteinHeart failureMolecular imagingPressure overload

Identifiers

PMID36171409
OpenAlexW4297515199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.