Evidence map›Paper›PMID 36171395›Full record

ArticleJournal of molecular evolution2022

Early Divergence of the C-Terminal Variable Region of Troponin T Via a Pair of Mutually Exclusive Alternatively Spliced Exons Followed by a Selective Fixation in Vertebrate Heart.

Tianxin Cao, Shirin Akhter, J-P Jin

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Tianxin CaoDepartment of Physiology and Biophysics, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Shirin AkhterDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
J-P JinDepartment of Physiology and Biophysics, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA. jpjin@uic.edu.ORCID 0000-0001-9932-1063
Illinois College · USUniversity of Illinois Chicago · USWayne State University · US

Funding

Regulation of Troponin I in Cardiac Adaptation & FailureR01HL127691 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2016 to 2026
$3.5M
Targeting Troponin T Regulation to Sustain Cardiac Function in Heart FailureR01HL138007 · NHLBI · WAYNE STATE UNIVERSITY · PI Jian-Ping Jin · 2018 to 2026
$2.4M
NHLBI NIH HHS R01 HL127691NHLBI NIH HHS R01 HL138007NIH HHS HL127691NIH HHS HL138007
6 · The paper itself

Abstract

Troponin T (TnT) is the thin filament anchoring subunit of troponin complex and plays an organizer role in the Ca

Indexed as

Caenorhabditis elegansTroponin TAnimalsDrosophilaExonsVertebratesTroponin TC-terminal variable region of troponin TDivergence of striated musclesMolecular evolutionSelective fixation of alternative exons

Identifiers

PMID36171395
PMCPMC10080876
OpenAlexW4297516991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.