ArticleScientific reports2022
Biosynthesis of copper oxide nanoparticles mediated Annona muricata as cytotoxic and apoptosis inducer factor in breast cancer cell lines.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 146 citations in OpenAlex.
- Copper/Copper Oxide Nanoparticles: Biological Synthesis, Characterization and Potential Biomedical Applications: Advances and Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Mechanistic paradigms of teratogenicity induced by metallic nanoparticles-a mini review.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Review
- Phyto mediated synthesis of copper oxide nanoparticles with Zingiber officinale: comprehensive bioactivity assessment against bacterial pathogens, cancer, and viruses.BMC biotechnology · 2026Article
- A Review on Silver Nanoparticles: Synthesis Approaches, Properties, Characterization and Applications.Pharmaceutical nanotechnology · 2026Review
- Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review).International journal of oncology · 2026Review
- Synthesis, characterization and bioactivity of chalcone-based polybenzoxazine/copper oxide nanocomposites.RSC advances · 2025Article
- Transformative potential of plant-based nanoparticles in cancer diagnosis and treatment: bridging traditional medicine and modern therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Alhagi maurorum: A Medicinal Treasure Trove Empowered by Copper Oxide Nanoparticles for Enhanced Secondary Metabolite Synthesis.Applied biochemistry and biotechnology · 2025Article
- Antimicrobial Potential of Nanomaterials Synthesized with Extracts fromAntibiotics (Basel, Switzerland) · 2025Review
- Investigation of antibiosis, anti-diabetic, antioxidant, anti-inflammatory, molecular docking and dye degradation potential of green synthesized copper ferrite (CuFeDiscover nano · 2025Article
- Interaction of Manganese-Doped Copper Oxide Nano-Platelets with Cells: Biocompatibility and Anticancer Activity Assessment.Biomimetics (Basel, Switzerland) · 2025Article
- Copper Nanoparticles Synthesized by Chemical Reduction with Medical Applications.International journal of molecular sciences · 2025Article
- Fabrication of zein nanofibrous scaffold containing Scrophularia striata extract for biomedical application.Journal of biological engineering · 2025Article
- Synthesis of chitosan/PVA/copper oxide nanocomposite using Anacardium occidentale extract and evaluating its antioxidant, antibacterial, anti-inflammatory and cytotoxic activities.Scientific reports · 2025Article
- Article
- Understanding the Molecular Toxicity of Metal-Based Nanoparticles Through Nanotoxicomics.International journal of nanomedicine · 2025Review
- Green synthesis of copper oxide nanoparticles via Moringa peregrina extract incorporated in graphene oxide: evaluation of antibacterial and anticancer efficacy.Bioprocess and biosystems engineering · 2024Article
- Biosynthesis of CuO nanoparticle using leaf extracts of Ocimum lamiifolium Hochst. ex Benth and Withana somnifera (L) Dunal for antibacterial activity.Scientific reports · 2024Article
- Green synthesis of copper oxide nanoparticles using walnut shell and their size dependent anticancer effects on breast and colorectal cancer cell lines.Scientific reports · 2024Article
- Biogenic nanoparticles: pioneering a new era in breast cancer therapeutics-a comprehensive review.Discover nano · 2024Review
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated for the first time a simple bio-synthesis approach for the synthesis of copper oxide nanoparticles (CuO NPs) using Annona muricata L (A. muricata) plant extract to test their anti-cancer effects. The presence of CuONPs was confirmed by UV-visible spectroscopy, Scanning electron microscope (SEM), and Transmission electron microscope (TEM). The antiproliferative properties of the synthesized nanoparticles were evaluated against (AMJ-13), (MCF-7) breast cancer cell lines, and the human breast epithelial cell line (HBL-100) as healthy cells. This study indicates that CuONPs reduced cell proliferation for AMJ-13 and MCF-7. HBL-100 cells were not significantly inhibited for several concentration levels or test periods. The outcomes suggest that the prepared copper oxide nanoparticles acted against the growth of specific cell lines observed in breast cancer. It was observed that cancer cells had minor colony creation after 24 h sustained CuONPs exposure using (IC
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