Evidence map›Paper›PMID 36171156›Full record

ArticleJournal of the American Pharmacists Association : JAPhA

Medication cost-reducing behaviors in older adults with atrial fibrillation: The SAGE-AF study.

Benita A Bamgbade, David D McManus, Becky A Briesacher, Darleen Lessard, Jordy Mehawej, Jerry H Gurwitz, Mayra Tisminetzky, Sarika Mujumdar, Weija Wang, Tanya Malihot and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Pharmacists Association : JAPhA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Benita A Bamgbade
David D McManus
Becky A Briesacher
Darleen Lessard
Jordy Mehawej
Jerry H Gurwitz
Mayra Tisminetzky
Sarika Mujumdar
Weija Wang
Tanya Malihot
Hawa O Abu
Molly Waring
Felix Sogade
Jeanne Madden
Isabelle C Pierre-Louis
Robert Helm
Robert Goldberg
Arthur F Kramer
Jane S Saczynski
Northeastern University · US

Funding

Detecting bleeding events using EHRs for prediction in AfibR01HL137794 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCMANUS, DAVID D., YU, HONG · 2018 to 2021
$3.3M
Systematic Assessment of Geriatric Elements in Atrial Fibrillation (SAGE-AF)R01HL126911 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCMANUS, DAVID D., SACZYNSKI, JANE STEELE · 2016 to 2019
$3.2M
Smartwatch Monitoring for Atrial Fibrillation After StrokeR01HL137734 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CHON, KI H, MCMANUS, DAVID D. · 2018 to 2021
$3.1M
FHS-NEXT - Framingham Novel EXam using TechnologyR01HL141434 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., MCMANUS, DAVID D. · 2019 to 2022
$2.5M
Clarifying the relationship between delirium and Alzheimer's Disease and relatedR33AG057979 · NIA · NORTHEASTERN UNIVERSITY · PI BRIESACHER, BECKY A · 2020 to 2021
$848k
Understanding Oral Anticoagulation Use and Success Among Patients with Psychiatric Multimorbidity in Atrial FibrillationK01HL155236 · NHLBI · NORTHEASTERN UNIVERSITY · PI BAMGBADE, BENITA A · 2021 to 2025
$808k
NHLBI NIH HHS K01 HL155236NHLBI NIH HHS L30 HL143689NHLBI NIH HHS R01 HL126911NHLBI NIH HHS R01 HL137734NHLBI NIH HHS R01 HL137794NHLBI NIH HHS R01 HL141434NIA NIH HHS R33 AG057979
6 · The paper itself

Abstract

backgroundAs patient prices for many medications have risen steeply in the United States, patients may engage in cost-reducing behaviors (CRBs) such as asking for generic medications or purchasing medication from the Internet.

objectiveThe objective of this study is to describe patterns of CRB, cost-related medication nonadherence, and spending less on basic needs to afford medications among older adults with atrial fibrillation (AF) and examine participant characteristics associated with CRB.

methodsData were from a prospective cohort study of older adults at least 65 years with AF and a high stroke risk (CHA

resultsAmong participants (N = 1224; mean age 76 years; 49% female), 69% reported engaging in CRB, 4% reported cost-related medication nonadherence, and 6% reported spending less on basic needs. Participants who were cognitively impaired (adjusted odds ratio 0.69 [95% CI 0.52-0.91]) and those who did not identify as non-Hispanic white (0.66 [0.46-0.95]) were less likely to engage in CRB. Participants who were married (1.88 [1.30-2.72]), had a household income of $20,000-$49,999 (1.52 [1.02-2.27]), had Medicare insurance (1.38 [1.04-1.83]), and had 4-6 comorbidities (1.43 [1.01-2.01]) had significantly higher odds of engaging in CRB.

conclusionAlthough CRBs were common among older adults with AF, few reported cost-related medication nonadherence and spending less on basic needs. Patients with cognitive impairment may benefit from pharmacist intervention to provide support in CRB and patient assistance programs.

Indexed as

Atrial FibrillationMedicareAgedFemaleHumansMaleMedication AdherenceProspective StudiesUnited States

Identifiers

PMID36171156
PMCPMC10699884
OpenAlexW4295012009

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.