ArticleEnvironmental health and preventive medicine2022
Association between daily ambient temperature and drug overdose in Tokyo: a time-series study.
Article in Environmental health and preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Extreme ambient temperature and emergency healthcare service utilization due to substance use disorders: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Association of short-term ambient environmental exposures with suicide and drug overdose deaths among U.S. veterans.American journal of epidemiology · 2026Article
- Temperature discomfort impairs everyday cognition: a pilot study using smartwatch-based ecological momentary assessment.Environmental research communications · 2026Article
- Extreme and moderate temperatures and risk of hospitalizations for pulmonary hypertension: an 11-year time-series study in Shanghai, China.Frontiers in medicine · 2026Article
- Spatial analysis of county-level determinants of overdose mortality in the United States using spatial machine learning.BMC public health · 2025Article
- Sociodemographic and clinical characteristics associated with overdose among patients with a substance-related diagnosis in the emergency department of Southern California.Harm reduction journal · 2025Article
- The association between hot days and substance-related suicides: a time-stratified case-crossover analysis in British Columbia, Canada.Environmental health : a global access science source · 2025Article
- Effects of apparent temperature on daily outpatient and inpatient visits for cause-specific respiratory diseases in Ganzhou, China: a time series study.Environmental health and preventive medicine · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have reported that high ambient temperature is associated with increased risk of suicide; however, the association has not been extensively investigated with drug overdose which is the most common method of unsuccessful suicidal behavior in Japan. Therefore, this study aims to examine the short-term association between daily mean temperature and the incidence of self-harm attempts by drug overdose in Tokyo, Japan.
methodsWe collected the emergency ambulance dispatch data and daily meteorological data in Tokyo from 2010 to 2014. A quasi-Poisson regression model incorporating a distributed lag non-linear function was applied to estimate the non-linear and delayed association between temperature and drug overdose, adjusting for relative humidity, seasonal and long-term trends, and days of the week. Sex, age and location-specific associations of ambient temperature with drug overdose was also estimated.
results12,937 drug overdose cases were recorded during the study period, 73.9% of which were female. We observed a non-linear association between temperature and drug overdose, with the highest risk observed at 21 °C. The highest relative risk (RR) was 1.30 (95% Confidence Interval (CI): 1.10-1.67) compared with the risk at the first percentile of daily mean temperature (2.9 °C) over 0-4 days lag period. In subgroup analyses, the RR of a drug overdose at 21 °C was 1.36 (95% CI: 1.02-1.81) for females and 1.07 (95% CI: 0.66-1.75) for males. Also, we observed that the risk was highest among those aged ≥65 years (RR = 2.54; 95% CI: 0.94-6.90), followed by those aged 15-34 years (RR = 1.25; 95% CI: 0.89-1.77) and those aged 35-64 years (RR = 1.15; 95% CI: 0.78-1.68). There was no evidence for the difference in RRs between urban (23 special wards) and sub-urban areas in Tokyo.
conclusionsAn increase in daily mean temperature was associated with increased drug overdose risk. This study indicated the positive non-linear association between temperature and incomplete attempts by drug overdose. The findings of this study may add further evidence of the association of temperature on suicidal behavior and suggests increasing more research and investigation of other modifying factors.
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