Evidence map›Paper›PMID 36171048›Full record

ArticleBMJ open2022

National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom.

Katie Evans, Cheryl Battersby, James P Boardman, Elaine M Boyle, William D Carroll, Kate Dinwiddy, Jon Dorling, Katie Gallagher, Pollyanna Hardy, Emma Johnston and 4 more

Abstract readConsensus Statement
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Katie EvansNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID 0000-0002-0503-9807
Cheryl BattersbyNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID 0000-0002-2898-553X
James P BoardmanMRC Centre for Reproductive Health, The University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-3904-8960
Elaine M BoyleNeonatal Medicine, Department of Health Sciences, University of Leicester, Leicester, UK.
William D CarrollDepartment of Paediatric Respiratory Medicine, University Hospitals of North Midlands, Stoke-on-Trent, UK.
Kate DinwiddyChief Executive of British Association of Perinatal Medicine, London, UK.
Jon DorlingNeonatal Medicine, University Hospital Southampton, Southampton, UK.
Katie GallagherChild and Adolescent Health, University College London, EGA Institute for Women's Health, London, UK.ORCID 0000-0002-6847-9594
Pollyanna HardyNational Perinatal Epidemiology Unit, Clinical Trials Unit, University of Oxford, Oxford, UK.
Emma JohnstonParents and Families Engagement Lead, Thames Valley and Wessex Operational Deliveries Network, Thames Valley and Wessex, UK.
Helen MactierNeonatal Medicine, University of Glasgow, Glasgow, UK.ORCID 0000-0001-6154-5758
Claire MarcroftPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
James WebbeNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID 0000-0001-8546-3212
Chris GaleNeonatal Medicine, School of Public Health, Faculty of Medicine, Imperial College London, London, UK christopher.gale@imperial.ac.uk.ORCID 0000-0003-0707-876X

Funding

Medical Research Council MR/N008405/1Medical Research Council MR/V036866/1
6 · The paper itself

Abstract

introductionMethodologically robust clinical trials are required to improve neonatal care and reduce unwanted variations in practice. Previous neonatal research prioritisation processes have identified important research themes rather than specific research questions amenable to clinical trials. Practice-changing trials require well-defined research questions, commonly organised using the Population, Intervention, Comparison, Outcome (PICO) structure. By narrowing the scope of research priorities to those which can be answered in clinical trials and by involving a wide range of different stakeholders, we aim to provide a robust and transparent process to identify and prioritise research questions answerable within the National Healthcare System to inform future practice-changing clinical trials. METHODS AND ANALYSIS: A steering group comprising parents, doctors, nurses, allied health professionals, researchers and representatives from key organisations (Neonatal Society, British Association of Perinatal Medicine, Neonatal Nurses Association and Royal College of Paediatrics and Child Health) was identified to oversee this project. We will invite submissions of research questions formatted using the PICO structure from the following stakeholder groups using an online questionnaire: parents, patients, healthcare professionals and academic researchers. Unanswered, non-duplicate research questions will be entered into a three-round eDelphi survey of all stakeholder groups. Research questions will be ranked by mean aggregate scores. ETHICS AND DISSEMINATION: The final list of prioritised research questions will be disseminated through traditional academic channels, directly to key stakeholder groups through representative organisations and on social media. The outcome of the project will be shared with key research organisations such as the National Institute for Health Research. Research ethics committee approval is not required.

Indexed as

Academies and InstitutesHealth PrioritiesDelphi TechniqueFemaleHumansInfant, NewbornPregnancyRandomized Controlled Trials as TopicSurveys and QuestionnairesUnited Kingdomneonatal intensive & critical careneonatologyprotocols & guidelines

Identifiers

PMID36171048
PMCPMC9528679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.