Evidence map›Paper›PMID 36170446›Full record

ArticleScience translational medicine2022

Improving breast cancer diagnostics with deep learning for MRI.

Jan Witowski, Laura Heacock, Beatriu Reig, Stella K Kang, Alana Lewin, Kristine Pysarenko, Shalin Patel, Naziya Samreen, Wojciech Rudnicki, Elżbieta Łuczyńska and 3 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Science translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07598084 (Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI), which is not on this map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
16.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07598084 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI: Development and Clinical Validation of a Diffusion-Weighted Imaging-Based Synthetic Contrast-Enhanced MRI System for Non-Contrast Breast Cancer Diagnosis and Risk Stratification

TypeobservationalSponsorPeking University People's HospitalRan2026 to 2027Enrolled12,000ConditionsBreast Neoplasms, Artificial Intelligence (AI), Magnetic Resonance Imaging (MRI), Diffusion Magnetic Resonance ImagingArmsNon-contrast breast MRI diagnostic model
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Application of artificial intelligence in laryngeal lesions: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
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  9. A deep learning model for automated identification of age-related macular degeneration atrophy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
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  11. Article
  12. Review
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Jan WitowskiDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-9284-4830
Laura HeacockDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-0900-0459
Beatriu ReigDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6577-8601
Stella K KangDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-2402-3787
Alana LewinDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Kristine PysarenkoDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Shalin PatelDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Naziya SamreenDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Wojciech RudnickiElectroradiology Department, Jagiellonian University Medical College, 31-126 Kraków, Poland.ORCID 0000-0003-2168-5638
Elżbieta ŁuczyńskaElectroradiology Department, Jagiellonian University Medical College, 31-126 Kraków, Poland.
Tadeusz PopielaChair of Radiology, Jagiellonian University Medical College, 31-501 Kraków, Poland.ORCID 0000-0002-6697-2449
Linda MoyDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-9564-9360
Krzysztof J GerasDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-0549-1446
New York University · USJagiellonian University · PLAdvanced Imaging Research (United States) · USCourant Institute of Mathematical Sciences · USNYU Langone Health · US

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Christopher M Collins · 2014 to 2026
$19.3M
Reducing recall rates of screening mammography with deep convolutional neural networkR21CA225175 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MOY, LINDA · 2018 to 2019
$395k
NCI NIH HHS R21 CA225175NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has a high sensitivity in detecting breast cancer but often leads to unnecessary biopsies and patient workup. We used a deep learning (DL) system to improve the overall accuracy of breast cancer diagnosis and personalize management of patients undergoing DCE-MRI. On the internal test set (

Indexed as

Breast NeoplasmsDeep LearningFemaleHumansMagnetic Resonance ImagingRetrospective StudiesROC Curve

Identifiers

PMID36170446
PMCPMC10323699
OpenAlexW4297502287

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.