Evidence map›Paper›PMID 36170252›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Altered VWF:ADAMTS13 homeostasis is a target for therapeutic intervention in sickle cell disease.

Shruti Chaturvedi, Michael R DeBaun

Open access · greenAbstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shruti ChaturvediDivision of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Michael R DeBaunVanderbilt-Meharry Center of Excellence in Sickle Cell Disease, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232.
Johns Hopkins University · USVanderbilt University Medical Center · US

Funding

ADAMTS13 and Late Neurologic Morbidity after Thrombotic Thrombocytopenic PurpuraK99HL150594 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHATURVEDI, SHRUTI · 2020 to 2023
$907k
NHLBI NIH HHS K99 HL150594
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle Cellvon Willebrand FactorADAMTS13 ProteinHomeostasisHumansADAMTS13 ProteinADAMTS13 protein, humanvon Willebrand Factor

Identifiers

PMID36170252
PMCPMC9546592
OpenAlexW4297456958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.