Evidence map›Paper›PMID 36170184›Full record

Observational studyJournal of addiction medicine

Missed Opportunities for HIV and Hepatitis C Screening Among Emergency Department Patients With Untreated Opioid Use Disorder.

Michael S Lyons, Marek C Chawarski, Richard Rothman, Lauren Whiteside, Ethan Cowan, Lynne D Richardson, Kathryn Hawk, Judith I Tsui, Robert P Schwartz, Patrick O'Connor and 3 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michael S LyonsFrom the Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH (MSL); Center for Addiction Research, University of Cincinnati College of Medicine, Cincinnati, OH (MSL); Department of Emergency Medicine, Yale School of Medicine, New Haven, CT (MCC, KH, GD, DAF); Department of Psychiatry, Yale School of Medicine, New Haven, CT (MCC); Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (RR); Department of Emergency Medicine, University of Washington School of Medicine, Seattle, WA (LW); Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, NY, NY (EC); Institute for Health Equity Research, Icahn School of Medicine at Mount Sinai, NY, NY (EC, LDR); Department of Medicine, University of Washington School of Medicine, Seattle, WA (JIT); Friends Research Institute, Baltimore, MD (RPS); Program in Addiction Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (PO, DAF, EJE); and Center for Interdisciplinary Research on AIDS, Yale School of Public Health, New Haven, CT (DAF, EJE).
Marek C Chawarski
Richard Rothman
Lauren Whiteside
Ethan Cowan
Lynne D Richardson
Kathryn Hawk
Judith I Tsui
Robert P Schwartz
Patrick O'Connor
Gail D'Onofrio
David A Fiellin
E Jennifer Edelman

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
NIDA NIH HHS UG1 DA015831
6 · The paper itself

Abstract

objectiveWe assessed the frequency of emergency department (ED) HIV and hepatitis C (HCV) screening in a high-risk cohort of ED patients with untreated opioid use disorder (OUD).

methodsThis analysis used data from a prospective, observational study of English-speaking adults with untreated OUD enrolled from April 2017 to December 2018 in 4 urban, academic EDs. Two cohorts were defined for this analysis by self-reported negative/unknown status for HIV (cohort 1) and HCV (cohort 2). Sites featured structured screening programs throughout the entire enrollment period for HIV and during at least part of the enrollment period for HCV. We calculated the proportion tested for HIV and HCV during the study enrollment ED visit.

resultsAmong 394 evaluated ED patients, 328 of 394 (83.2%) were not tested for HIV or HCV and 244 of 393 (62.1%) lacked a usual medical care provider. In cohort 1, 375 reported negative or unknown HIV status; 59/375 (15.7%) overall and 33/218 (15.1%) of those reporting recent injection drug use were tested for HIV. In cohort 2, 231 reported negative of unknown HCV status; 22/231 (9.5%) overall and 9/98 (9.2%) of those reporting recent injection drug use were tested for HCV. The proportion tested by the ED ranged from 3% to 25% for HIV and 4% to 32% for HCV across study sites.

conclusionsEmergency department HIV and HCV screening remains infrequent among patients with untreated OUD, including those who inject drugs, even in EDs committed to screening. Targeted HIV/HCV screening should be considered as an adjunct strategy until the ideal of universal screening is more fully achieved.

Indexed as

Hepatitis CHIV InfectionsOpioid-Related DisordersAdultEmergency Service, HospitalHepacivirusHumansProspective Studies

Identifiers

PMID36170184
PMCPMC10023471

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.