ArticleAging2022
Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults.
Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- A clinically practical aging clock (physical clock) for healthy aging: development, validation, and application for health assessment and intervention.Science China. Life sciences · 2026Article
- The Evolving Landscape of Clinical Aging Clocks: From Epigenetic to Multi-Omics Integration.Aging cell · 2026Review
- Longitudinal association of ultra-processed food consumption with biological aging: the mediating role of adiposity measures.GeroScience · 2026Article
- Latent biochemical phenotypes delineate divergent health trajectories in older adults.npj aging · 2026Article
- Divergent impacts of estradiol/testosterone reduction on biological aging: optimal HRT window in females recommended.Biology of sex differences · 2026Article
- Blood biochemical and gut microbiotic neural network models forecasting human biological age.Aging · 2026Article
- Molecular pathways linking chronic psychological stress to accelerated aging: mechanisms and interventions.Frontiers in aging · 2026Review
- Molecular markers, mechanisms and metrics of biological aging: a scoping review.Frontiers in aging · 2026Review
- Predicting older adults smart healthcare adoption using an extended TAM.Scientific reports · 2025Article
- Impact of early-life food deprivation on health-related quality of life among older people in China: evidence from CHARLS.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank.Scientific reports · 2025Article
- Regulation of cellular senescence in tumor progression and therapeutic targeting: mechanisms and pathways.Molecular cancer · 2025Review
- Correlation Between Dental Age, Chronological Age, and Cervical Vertebral Maturation in Patients with Class II Malocclusion: A Retrospective Study in a Romanian Population Group.Children (Basel, Switzerland) · 2025Article
- Deep learning and generative artificial intelligence in aging research and healthy longevity medicine.Aging · 2025Review
- Do single people age faster? The answer may lie in sleep.Frontiers in aging · 2025Article
- Promising benefits of six-monthFrontiers in aging · 2025Article
- Article
- Metabolomic age (MileAge) predicts health and life span: A comparison of multiple machine learning algorithms.Science advances · 2024Article
- Review
- The association between blood biological age at rehabilitation admission and physical activity during rehabilitation in geriatric inpatients: RESORT.GeroScience · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have developed a deep learning aging clock using blood test data from the China Health and Retirement Longitudinal Study, which has a mean absolute error of 5.68 years. We used the aging clock to demonstrate the connection between the physical and psychological aspects of aging. The clock detects accelerated aging in people with heart, liver, and lung conditions. We demonstrate that psychological factors, such as feeling unhappy or being lonely, add up to 1.65 years to one's biological age, and the aggregate effect exceeds the effects of biological sex, living area, marital status, and smoking status. We conclude that the psychological component should not be ignored in aging studies due to its significant impact on biological age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.