Evidence map›Paper›PMID 36169684›Full record

ArticleSocial psychiatry and psychiatric epidemiology2023

Pre-pandemic resilience to trauma and mental health outcomes during COVID-19.

Karmel W Choi, Kristen Nishimi, Shaili C Jha, Laura Sampson, Jill Hahn, Jae H Kang, Karestan C Koenen, Laura D Kubzansky

Open access · bronzeAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  13. Fear of COVID-19, Perceived Stress, and PTSD: The Serial Mediating Role of Sense of Coherence.European journal of investigation in health, psychology and education · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Karmel W Choi *Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA. kwchoi@mgh.harvard.edu.
Kristen Nishimi *Mental Health Service, San Francisco Veterans Affairs Health Care System, San Francisco, CA, USA. kristen.nishimi@ucsf.edu.ORCID http://orcid.org/0000-0001-6189-830X
Shaili C JhaDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Laura SampsonDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Jill HahnDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Jae H KangChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Karestan C KoenenCenter for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Laura D KubzanskyDepartment of Social and Behavioral Sciences and Lee Kum Sheung Center for Health and Happiness, Harvard TH Chan School of Public Health, Boston, MA, USA.
Harvard University · USBrigham and Women's Hospital · USMassachusetts General Hospital · USUniversity of California, San Francisco · US

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
CVD Epidemiology Training Program in Behavior, the Environment and Global HealthT32HL098048 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Goodarz Danaei, ERIC B RIMM · 2009 to 2026
$6.9M
Post Traumatic Stress Disorder and Accelerated Aging in WomenR01MH101269 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C, KUBZANSKY, LAURA D · 2014 to 2021
$6.5M
Genetic Determinants of PTSD in WomenR01MH078928 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C · 2007 to 2010
$2.9M
Integrating Health Records, Genomic, and Social Data to Stratify Adolescent Depression RiskK08MH127413 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, KARMEL · 2021 to 2025
$987k
Brain and Behavior Research Foundation NARSAD Young Investigator GrantHarvard T.H. Chan School of Public Health Dean's Fund for Scientific AdvancementNCI NIH HHS U01 CA176726NHLBI NIH HHS T32 HL098048NIH HHS U01 CA176726NIMH NIH HHS K08 MH127413NIMH NIH HHS R01MH078928NIMH NIH HHS R01MH101269NIMH NIH HHS T32 MH017119NIMH NIH HHS T32 MH017119-33Office of Academic Affiliations, Department of Veterans Affairs Data Science FellowshipU.S. Department of Defense W81XWH-17-1-0153
6 · The paper itself

Abstract

purposeThe stress-sensitization hypothesis posits that individuals with prior trauma are at elevated risk for poor mental health when faced with subsequent stressors. Little work has examined whether those who have demonstrated psychological resilience to prior trauma would show either increased resilience or vulnerability to subsequent stressors. We examined pre-pandemic psychological resilience to lifetime trauma in relation to mental health outcomes amid the coronavirus disease 2019 (COVID-19) pandemic, a major societal stressor.

methodsThe sample included 16,900 trauma-exposed women from the Nurses' Health Study II. Pre-pandemic resilience was defined by psychological health in 2017-2019 (characterized by levels of both distress and positive emotional well-being) relative to lifetime trauma. Resilience was defined categorically by cross-classifying unfavorable, adequate, and favorable psychological health by higher versus lower trauma burden, and continuously as the residual difference in predicted versus actual psychological health regressed on trauma burden. Mental health outcomes as of May-August 2020 included psychological distress symptoms and overall positive emotional well-being. Associations were assessed using covariate-adjusted regression models.

resultsPre-pandemic resilience was associated with lower distress and higher well-being early in the COVID-19 pandemic. Relative to the women showing highest resilience (favorable psychological health despite higher trauma), only those with lower trauma and favorable prior psychological health had significantly lower distress and higher positive emotional well-being during the pandemic. Higher continuous pre-pandemic resilience was also significantly associated with lower distress and higher positive emotional well-being during the pandemic.

conclusionPreventing mental health problems following trauma may contribute to protecting population well-being amid major stressors.

Indexed as

COVID-19Resilience, PsychologicalEmotionsFemaleHumansMental HealthOutcome Assessment, Health CarePandemicsCOVID-19LongitudinalMental healthPsychological resilienceTrauma

Identifiers

PMID36169684
PMCPMC9514982
OpenAlexW4297459433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.