Evidence map›Paper›PMID 36169668›Full record

ArticlePediatric radiology2023

Microfocus computed tomography for fetal postmortem imaging: an overview.

Daniël Docter, Yousif Dawood, Karl Jacobs, Jaco Hagoort, Roelof-Jan Oostra, Maurice J B van den Hoff, Owen J Arthurs, Bernadette S de Bakker

Open access · hybridFull text read
In one paragraph

Article in Pediatric radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. High-resolution 3D micro-CT reveals an additional muscle layer in esophageal atresia.Esophagus : official journal of the Japan Esophageal Society · 2026
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  10. Whole-body non-forensic fetal virtopsy using postmortem magnetic resonance imaging at 7 Tesla vs classical autopsy.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Daniël DocterDepartment of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.
Yousif DawoodDepartment of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.
Karl JacobsDepartment of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.
Jaco HagoortDepartment of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.
Roelof-Jan OostraDepartment of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.
Maurice J B van den HoffDepartment of Medical Biology, Amsterdam UMC at University of Amsterdam, Amsterdam, The Netherlands.
Owen J ArthursDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Bernadette S de BakkerDepartment of Obstetrics and Gynecology, Amsterdam UMC at University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. b.s.debakker@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-0758-4064
Amsterdam University Medical Centers · NLAcademic Center for Dentistry Amsterdam · NLAmsterdam Neuroscience · NLGreat Ormond Street Hospital · GB

Funding

Medical Research Council MR/R002118/1
6 · The paper itself

Abstract

Over the last few years, fetal postmortem microfocus computed tomography (micro-CT) imaging has increased in popularity for both diagnostic and research purposes. Micro-CT imaging could be a substitute for autopsy, particularly in very early gestation fetuses for whom autopsy can be technically challenging and is often unaccepted by parents. This article provides an overview of the latest research in fetal postmortem micro-CT imaging with a focus on diagnostic accuracy, endovascular staining approaches, placental studies and the reversibility of staining. It also discusses new methods that could prove helpful for micro-CT of larger fetuses. While more research is needed, contrast-enhanced micro-CT has the potential to become a suitable alternative to fetal autopsy. Further research using this novel imaging tool could yield wider applications, such as its practise in imaging rare museum specimens.

Indexed as

FetusPlacentaAutopsyFemaleGestational AgeHumansMagnetic Resonance ImagingPregnancyX-Ray MicrotomographyAnatomyAutopsyDiffusible iodine-based contrast-enhanced computed tomographyFetusHumanIntrauterine fetal demiseMicrofocus computed tomographyPostmortemStillbirth

Identifiers

PMID36169668
PMCPMC10027643
OpenAlexW4297458494

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read22
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.