Evidence map›Paper›PMID 36169304›Full record

ArticleeLife2022

The SPARC complex defines RNAPII promoters in

Desislava P Staneva, Stefan Bresson, Tatsiana Auchynnikava, Christos Spanos, Juri Rappsilber, A Arockia Jeyaprakash, David Tollervey, Keith R Matthews, Robin C Allshire

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Mapping Open Chromatin in Trypanosoma brucei Using ATAC-Seq.Methods in molecular biology (Clifton, N.J.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Desislava P StanevaWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-1330-2158
Stefan BressonWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0002-0329-2243
Tatsiana AuchynnikavaWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.
Christos SpanosWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0002-4376-8242
Juri RappsilberWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.
A Arockia JeyaprakashWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.
David TollerveyWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-2894-2772
Keith R MatthewsInstitute of Immunology and Infection Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-0309-9184
Robin C AllshireWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0002-8005-3625
Wellcome Centre for Cell Biology · GBInstitute of Immunology · HRCzech Academy of Sciences, Institute of Biotechnology · CZThe Francis Crick Institute · GB

Funding

Medical Research Council MR/T04702X/1Wellcome Trust 108504Wellcome Trust 200885Wellcome Trust 200885/Z/16/ZWellcome Trust 202811Wellcome Trust 202811/Z/16/ZWellcome Trust 203149Wellcome Trust 22171Wellcome Trust 221717Wellcome Trust 221717/Z/20/ZWellcome Trust 222516Wellcome Trust 224358
6 · The paper itself

Abstract

Kinetoplastids are a highly divergent lineage of eukaryotes with unusual mechanisms for regulating gene expression. We previously surveyed 65 putative chromatin factors in the kinetoplastid

Indexed as

Trypanosoma brucei bruceiChromatinHeterochromatinHistone MethyltransferasesRNA, MessengerRNA Polymerase IITranscription, GeneticVariant Surface Glycoproteins, TrypanosomaChromatinHeterochromatinHistone MethyltransferasesRNA, MessengerRNA Polymerase IIVariant Surface Glycoproteins, Trypanosomachromatinchromosomesgene expressionhistonesKinetoplastidpromoterstranscriptiontranscriptional start regionsTrypanosoma brucei

Identifiers

PMID36169304
PMCPMC9566855
OpenAlexW4297458009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.