ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2024
Sensory Loss and Risk of Dementia.
Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Hearing Loss, Cognitive Decline, and Dementia: Clinical Intersections.Audiology research · 2026Review
- Improving cognitive performance through adaptive audiovisual perceptual training in community-dwelling older adults.BMC geriatrics · 2026Article
- Comorbidities in Age-Related Cataract: Epidemiological Burden and Public Health Implications.Vision (Basel, Switzerland) · 2026Review
- Dynamic thermodynamic-informational entropic relationship (TIER) models of selective vulnerability to neurodegeneration.bioRxiv : the preprint server for biology · 2026Article
- Trajectories of cognitive decline before and after new-onset dual sensory impairment: findings from two longitudinal studies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Differences in hearing across the lifespan in two strains of Alzheimer's mouse models as measured using behavioral and physiological techniques.Hearing research · 2026Article
- Cognitive effects of untreated unilateral and bilateral hearing loss in midlife: Preliminary evidence.PloS one · 2026Article
- Screening cognitive decline in older adults using umami hypogeusia and oral diadochokinesis: a cross-sectional study.BMC geriatrics · 2025Article
- Cognitive and Behavioural Associations of Visual and Hearing Impairments Across the Lifespan in People With Down Syndrome, a Scoping Review.Journal of intellectual disability research : JIDR · 2025Article
- Impact of Hearing Loss on Memory Loss in Patients With Self-Reported Olfactory Dysfunction.Cureus · 2025Article
- The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system.Acta neuropathologica · 2025Article
- Article
- Unraveling the Enigma: Exploring the Periphery's Influence in Alzheimer's Pathophysiology-Cause or Consequence?The Eurasian journal of medicine · 2025Article
- Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts.Frontiers in aging neuroscience · 2025Article
- INTegRated InterveNtion of pSychogerIatric Care: real-world application and implementation of an advanced integrated telehealth system incorporating machine learning.Frontiers in psychology · 2025Article
- Aging-associated sensory decline and Alzheimer's disease.Molecular neurodegeneration · 2024Review
- Subjective hearing loss is not associated with an increased risk of Alzheimer's disease dementia.Heliyon · 2024Article
- Dual sensory impairments in companion dogs: Prevalence and relationship to cognitive impairment.PloS one · 2024Article
- Functional Connectivity Favors Aberrant Visual Network c-Fos Expression Accompanied by Cortical Synapse Loss in a Mouse Model of Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Article
- Blue Light Filtration in Intraocular Lenses: Effects on Visual Function and Systemic Health.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Sensory loss in olfaction, vision, and hearing is a risk factor for dementia, but the reasons for this are unclear. This review presents the neurobiological evidence linking each sensory modality to specific dementias and explores the potential mechanisms underlying this. Olfactory deficits can be linked to direct neuropathologic changes in the olfactory system due to Alzheimer disease and Parkinson disease, and may be a marker of disease severity. Visual deficits potentially increase dementia risk in a vulnerable individual by reducing resilience to dementia. Hearing deficits may indicate a susceptibility to Alzheimer disease through a variety of mechanisms. More generally, sensory impairment could be related to factors associated with resilience against dementia. Further research is needed to tease out the specific and synergistic effects of sensory impairment. Studying sensory loss in relation to neurodegenerative biomarkers is necessary to clarify the mechanisms involved. This could produce new monitoring and management strategies for people at risk of dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.