Evidence map›Paper›PMID 36169259›Full record

ArticleImmunity, inflammation and disease2022

Monocyte-derived macrophages: The supplements of hepatic macrophage in Echinococcus multilocularis infected mice.

Bin Li, Xinwei Qi, Yumei Liu, Yi Yan, Jiaoyu Shan, Xuanlin Cai, Jie Lv, Xuan Zhou, Tao Yu, Xiumin Ma

Open access · goldAbstract read
In one paragraph

Article in Immunity, inflammation and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Immune modulation of Th1/Th2/Treg/Th17/Th9/Th21 cells in rabbits infected withFrontiers in cellular and infection microbiology · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Bin LiState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, China.
Xinwei QiDepartment of Hepatic Hydatid, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Yumei LiuDepartment of Hepatic Hydatid, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Yi YanDepartment of Hepatic Hydatid, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Jiaoyu ShanBasic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.
Xuanlin CaiDepartment of Hepatic Hydatid, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Jie LvState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, China.
Xuan ZhouState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, China.
Tao YuShandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, China.
Xiumin MaState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, China.ORCID 0000-0001-8011-7513
Xinjiang Medical University · CNShandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlveolar echinococcosis is a potentially lethal zoonosis caused by the cestode Echinococcus multilocularis. This study is to investigate the dynamic changes of monocytes, macrophages, and related cytokines in animal models of persistent infection of E. multilocularis.

methodsAn infection model was established by intraperitoneal injection of a protoscolex suspension. The pathological changes of liver were observed by HE staining. The percentage of Ly6C

resultsHematoxylin-eosin(HE) staining showed that significant lesions appeared in the later stages of infection in the liver. The proportion of Ly6C

conclusionsMonocytes as a supplement to hepatic macrophage, monocytes and kupffer cells may both participate in Th1 and Th2 immune responses by differentiating into M1 or M2 at different stages of E. multilocularis infection.

Indexed as

Echinococcus multilocularisAnimalsCytokinesEosine Yellowish-(YS)HematoxylinInterleukin-10Interleukin-17Interleukin-4Kupffer CellsMacrophagesMiceRNA, MessengerTumor Necrosis Factor-alphaCytokinesEosine Yellowish-(YS)HematoxylinInterleukin-10Interleukin-17Interleukin-4RNA, MessengerTumor Necrosis Factor-alphaEchinococcus multilocularis infectionkupffer cellsmonocyte-derived macrophages

Identifiers

PMID36169259
PMCPMC9511960
OpenAlexW4297220550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.