Evidence map›Paper›PMID 36169197›Full record

ArticlemBio2022

Genetic Divergence of Vibrio vulnificus Clinical Isolates with Mild to Severe Outcomes.

Kendall Kling, Sonya A Trinh, Semen A Leyn, Dmitry A Rodionov, Ivan D Rodionov, Alfa Herrera, Kasey Cervantes, George Pankey, Deborah Ashcraft, Egon A Ozer and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Phylogenetic Characterization ofFoodborne pathogens and disease · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Public health aspects ofEFSA journal. European Food Safety Authority · 2024
    Article
  8. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Antibiotic resistance trends amongApplied and environmental microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Kendall KlingDivision of Infectious Diseases, Department of Medicine, Northwestern Universitygrid.16753.36 Feinberg School of Medicine, Chicago, Illinois, USA.
Sonya A TrinhDivision of Infectious Diseases, Ochsner Medical Centergrid.240416.5, New Orleans, Louisiana, USA.ORCID 0000-0002-8328-4867
Semen A LeynSanford Burnham Prebys Medical Discovery Institute, LaJolla, California, USA.ORCID 0000-0002-9886-9120
Dmitry A RodionovSanford Burnham Prebys Medical Discovery Institute, LaJolla, California, USA.
Ivan D RodionovUniversity of California, San Diego, La Jolla, California, USA.
Alfa HerreraDivision of Infectious Diseases, Department of Medicine, Northwestern Universitygrid.16753.36 Feinberg School of Medicine, Chicago, Illinois, USA.
Kasey CervantesDivision of Infectious Diseases, Department of Medicine, Northwestern Universitygrid.16753.36 Feinberg School of Medicine, Chicago, Illinois, USA.
George PankeyInfectious Disease Translational Research, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
Deborah AshcraftInfectious Disease Translational Research, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
Egon A OzerDivision of Infectious Diseases, Department of Medicine, Northwestern Universitygrid.16753.36 Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-7131-3691
Adam GodzikBiosciences Division, University of California Riverside School of Medicine, Riverside, California, USA.
Karla J F SatchellDepartment of Microbiology-Immunology, Northwestern Universitygrid.16753.36 Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-3274-7611
Northwestern University · USOchsner Medical Center · USSanford Burnham Prebys Medical Discovery Institute · USUniversity of California, Riverside · USUniversity of California San Diego · US

Funding

Molecular mechanism of V. vulnificus MARTX toxin in pathogenesis and food safetyR01AI092825 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SATCHELL, KARLA J F · 2011 to 2021
$4.1M
Vibrio MARTX toxin effectors in signaling and pathogenesisR37AI092825 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Karla J F Satchell · 2022 to 2026
$2.5M
Translational Research Training in Infectious DiseasesT32AI095207 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Claudia A Hawkins, Jennie H Kwon · 2012 to 2026
$2.2M
Function of Vibrio vulnificus MARTX toxin during early gut infectionR01AI098369 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SATCHELL, KARLA J F · 2012 to 2016
$1.3M
NIAID NIH HHS HHSN272201400027CNIAID NIH HHS R01 AI092825NIAID NIH HHS R01 AI098369NIAID NIH HHS R37 AI092825NIAID NIH HHS T32 AI095207
6 · The paper itself

Abstract

The marine bacterium Vibrio vulnificus infects humans via food or water contamination, leading to serious manifestations, including gastroenteritis, wound infections, and septic shock. Previous studies suggest phylogenetic Lineage 1 isolates with the v

Indexed as

Bacterial ToxinsVibrio vulnificusAnimalsGenetic DriftHumansMicePhylogenyBacterial Toxinsgenomepatient outcomephylogenyRTX toxinssurveillancetoxinVibrio vulnificus

Identifiers

PMID36169197
PMCPMC9600620
OpenAlexW4297457121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.