ArticleAnnals of medicine2022
Evaluating the impact of naloxone dispensation at public health vending machines in Clark County, Nevada.
Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: a systematic review.Harm reduction journal · 2025Pooled it
- Daily polysubstance use associated with HIV, HCV, and non-fatal overdose among people who inject drugs: A latent class analysis using nationwide data.Drug and alcohol dependence · 2026Article
- Harm Reduction Vending Machines in Supportive Housing for Veterans.JAMA network open · 2026Article
- "Smart" harm reduction vending machines to improve public health: Evaluating the utilization.Journal of substance use and addiction treatment · 2026Article
- An Epidemic of Complexity: Polysubstance Use Fatal Overdose Typologies Across Cook County, Illinois, Neighborhoods, 2017‒2022.American journal of public health · 2026Article
- National review of state laws on opioid antagonists in Kindergarten-12th grade schools across the United States.Harm reduction journal · 2026Review
- Exploring Perspectives About Public Health Vending Machine Implementation on an American Indian Reservation in the Northern Midwest, United States.AIDS and behavior · 2026Article
- Substance use treatment and overdose patterns in high and low social vulnerability counties: a trends analysis in New Jersey from 2014-2022.Addictive behaviors reports · 2026Article
- Syringe service program utilization, behavioral, and experiential factors associated with greater naloxone protection in a longitudinal cohort of people who use illicit opioids in New York city.Harm reduction journal · 2026Article
- Expanding PrEP Access Through Decentralized Delivery Models.Current HIV/AIDS reports · 2026Review
- Patterns of polysubstance use among people who use drugs on an American Indian reservation of a southern plains Tribal Nation.Harm reduction journal · 2026Article
- Applying the Consolidated Framework for Implementation Research (CFIR) to understand college health administrator perceptions on adopting and implementing opioid overdose education and naloxone distribution (OEND) programs among universities nationally.Harm reduction journal · 2026Article
- Acceptability and Appropriateness of Harm Reduction Vending Machines Compared to Syringe Service Programs in Appalachian Kentucky.Journal of studies on alcohol and drugs · 2026Article
- Expanding access to harm reduction in rural communities through community-informed public health vending machines.Harm reduction journal · 2026Article
- Evaluating the implementation and impact of harm reduction vending machines in veterans supportive housing settings: a mixed-methods study protocol.Harm reduction journal · 2026Article
- Breaking barriers: evaluating access models for harm reduction vending machines.The International journal on drug policy · 2026Article
- Preferences for harm reduction vending machine design among rural people who use drugs.Drug and alcohol dependence reports · 2025Article
- Syringe Service Program Utilization, Behavioral, and Experiential Factors Associated with Greater Naloxone Protection in a Longitudinal Cohort of People Who Use Illicit Opioids in New York City.Research square · 2025Article
- Increasing opportunities for community input in harm reduction program development using iterative engagement.Harm reduction journal · 2025Review
- Discreet but accessible: a qualitative study with people who use drugs and service staff about the optimal design of a harm reduction vending machine in rural Kentucky.Harm reduction journal · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
introductionImplementing public health vending machines (PHVMs) is an evidence-based strategy for mitigating substance use-associated morbidity and mortality
methodsMonthly counts of opioid-involved overdose fatalities among Clark County residents that occurred from January 2015 to December 2020 were used to build an autoregressive integrated moving averages (ARIMA) model to measure the impact of naloxone dispensation at PHVMs. We forecasted the number of expected opioid-involved overdose fatalities had naloxone dispensation at PHVMs not occurred and compared to observed monthly counts. Interrupted time series analyses (ITSA) were used to evaluate the step (i.e. the immediate impact of naloxone dispensation at PHVMs on opioid-involved overdose fatalities) and slope change (i.e. changes in trend and directionality of monthly counts of opioid-involved overdose fatalities following naloxone dispensation at PHVMs).
resultsDuring the 12-months immediately following naloxone dispensation at PHVMs, our model forecasted 270 opioid-involved overdose fatalities, but death certificate data indicated only 229 occurred, suggesting an aversion of 41 deaths. ITSA identified a significant negative step change in opioid-involved overdose fatalities at the time naloxone dispensation at PHVMs was launched (B = -8.52,
conclusionNaloxone dispensation at PHVMs was associated with immediate reductions in opioid-involved overdose fatalities. Key MessagesNaloxone dispensation at PHVMs was associated with immediate reductions in opioid-involved overdose fatalities.Communities should consider implementing public health vending machines in efforts to prevent opioid-involved overdose fatalities.The COVID-19 pandemic worsened the overdose crisis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.