Evidence map›Paper›PMID 36168850›Full record

ArticleJournal of separation science2022

Human serum N-glycome profiling via the newly developed asparagine immobilized cellulose/polymer nanohybrid.

Muhammad Salman Sajid, Muhammad Nakash Saleem, Fahmida Jabeen, Shafaq Saleem, Sabeen Iqbal, Shahid Habib, Muhammad Naeem Ashiq, Habtom W Ressom, Muhammad Najam-Ul-Haq

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of separation science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Muhammad Salman SajidDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Muhammad Nakash SaleemDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Fahmida JabeenDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Shafaq SaleemDepartment of Chemistry, The Women University, Multan, Pakistan.
Sabeen IqbalDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Shahid HabibDepartment of Pathology, Nishtar Medical University, Multan, Pakistan.
Muhammad Naeem AshiqDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Habtom W RessomDepartment of Oncology, Genomics and Epigenomics Shared Resource, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, USA.
Muhammad Najam-Ul-HaqDivision of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.ORCID https://orcid.org/0000-0002-2090-5072
Bahauddin Zakariya University · PKGeorgetown University · USNishtar Medical College and Hospital · PKThe Women University Multan · PK

Funding

Systems Metabolomics for Biomarker DiscoveryR35GM141944 · NIGMS · GEORGETOWN UNIVERSITY · PI RESSOM, HABTOM W · 2021 to 2025
$2.4M
Analysis of Racial Disparities in HCC by Systems MetabolomicsU01CA185188 · NCI · GEORGETOWN UNIVERSITY · PI RESSOM, HABTOM W · 2015 to 2019
$1.7M
NCI NIH HHS U01 CA185188NIGMS NIH HHS R35 GM141944
6 · The paper itself

Abstract

Human serum N-linked glycans expression levels change during the disease progression. The low abundance, structural diversity, and coexisting matrices hinder their detection in mass spectrometry analysis. Considering the hydrophilic nature of N-glycans, cellulose/polymer (1,2-Epoxy-5-hexene) nanohybrid is fabricated with oxirane groups functionalized of asparagine to develop solid phase extraction based hydrophilic interaction liquid chromatography sorbent (cellulose/1,2-Epoxy-5-hexene/asparagine). The morphology, elemental analysis, and surface properties are studied through scanning electron microscopy, energy dispersive X-ray spectroscopy, and Fourier-transform infrared spectroscopy. The large surface area of cellulose/polymer nanohybrid (2.09 × 10

Indexed as

CellulosePolymersAsparagineEpoxy CompoundsHumans1,2-epoxy-5-hexeneAsparagineCelluloseEpoxy CompoundsPolymerscellulosehuman serumhydrophilic interaction liquid chromatographymass spectrometryN-linked glycans

Identifiers

PMID36168850
PMCPMC9812403
OpenAlexW4297459710

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.