Evidence map›Paper›PMID 36168640›Full record

ArticleHealth psychology research2022

Gender Dysphoria and Its Non-Surgical and Surgical Treatments.

Danyon Anderson, Himasa Wijetunge, Peyton Moore, Daniel Provenzano, Nathan Li, Jamal Hasoon, Omar Viswanath, Alan D Kaye, Ivan Urits

Abstract read
In one paragraph

Article in Health psychology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Gender-Affirming Bilateral Orchiectomy for the Urogynecologist.International urogynecology journal · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. MANAGEMENT OF GENDER-AFFIRMING PATIENTS - A PLASTIC SURGERY PERSPECTIVE.Acta endocrinologica (Bucharest, Romania : 2005)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danyon AndersonMedical School, Medical College of Wisconsin.
Himasa WijetungeSchool of Medicine, Louisiana State University Health Sciences Center.
Peyton MooreSchool of Medicine, Louisiana State University Health Science Center.
Daniel ProvenzanoSchool of Medicine, Louisiana State University Health Sciences Center.
Nathan LiMedical School, Medical College of Wisconsin.
Jamal HasoonAnesthesiology, Beth Israel Deaconess Medical Center, Harvard Medical School.
Omar ViswanathSchool of Medicine, Louisiana State University Health Sciences Center.
Alan D KayeSchool of Medicine, Louisiana State University Health Sciences Center.
Ivan UritsSchool of Medicine, Louisiana State University Health Sciences Center.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gender dysphoria is defined by severe or persistent distress associated with an incongruence between one's gender identity and biological sex. It is estimated that 1.4 million Americans and 25 million people worldwide identify as transgender and that 0.6% of Americans experience gender dysphoria. The pathophysiology of gender dysphoria is multifactorial and incompletely understood. Genetics, androgen exposure, neuroanatomy, brain connectivity, history of trauma, parents with psychological disorders, and being raised by less than two parents are associated with gender dysphoria. Gender dysphoria most frequently presents in early teenage years but can present earlier or later. Anxiety and depression are the two most common comorbid diagnoses and may be the reason for presentation to medical care. Diagnosis is established through history and or validated questionnaires. Treatment includes psychosocial therapy, pharmacotherapy for underlying depression and/or anxiety, hormonal therapy, non-genital and/or genital feminization or masculinization operations. The frequency and severity of treatment related morbidity increases progressively as treatments go from conservative to more invasive. Gender dysphoria and its treatment is individualized and not completely understood.

Indexed as

feminization surgerygender affirmation surgeryGender dysphoriahormone replacement therapymasculinization surgerytransgender

Identifiers

PMID36168640
PMCPMC9501960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.