Evidence map›Paper›PMID 36168634›Full record

ArticleTheranostics2022

Circular RNA cancer vaccines drive immunity in hard-to-treat malignancies.

Hongjian Li, Kun Peng, Kai Yang, Wenbo Ma, Shaolong Qi, Xinyang Yu, Jia He, Xin Lin, Guocan Yu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 214 citations in OpenAlex.

  1. Review
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  10. Therapy resistance-related ncRNAs in cervical cancer: biomarkers and therapeutic targets.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Review
  11. In the age of mRNA vaccines: Linear or circular mRNA?Molecular therapy. Nucleic acids · 2026
    Article
  12. Review
  13. Review
  14. IVT-free, chemically synthesized protein-encoding RNA oligonucleotides for rapid production of personalized cancer vaccines.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hongjian LiInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.
Kun PengInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.
Kai YangKey Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Wenbo MaInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.
Shaolong QiKey Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Xinyang YuKey Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Jia HeSchool of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.
Xin LinInstitute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.
Guocan YuKey Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Tsinghua University · CNCenter for Life Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer VaccinesNanoparticlesNeoplasmsAnimalsLiposomesMicemRNA VaccinesRNARNA, CircularRNA, MessengerVaccines, SyntheticCancer VaccinesLipid NanoparticlesLiposomesmRNA VaccinesRNARNA, CircularRNA, MessengerVaccines, Syntheticcancer vaccinescircular RNAhard-to-treat malignancieslipid nanoparticlestumor immunotherapy

Identifiers

PMID36168634
PMCPMC9475446
OpenAlexW4295222570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.