Evidence map›Paper›PMID 36168513›Full record

ArticleIEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society2020

Optical Coherence Tomography-Guided Robotic Ophthalmic Microsurgery via Reinforcement Learning from Demonstration.

Brenton Keller, Mark Draelos, Kevin Zhou, Ruobing Qian, Anthony Kuo, George Konidaris, Kris Hauser, Joseph Izatt

Open access · hybridAbstract read
In one paragraph

Article in IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 72 citations in OpenAlex.

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  6. An intuitive guidewire control mechanism for robotic intervention.International journal of computer assisted radiology and surgery · 2025
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  16. Simultaneous Online Registration-Independent Stiffness Identification and Tip Localization of Surgical Instruments in Robot-assisted Eye Surgery.IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Brenton KellerDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Mark DraelosDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Kevin ZhouDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Ruobing QianDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Anthony KuoDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA.
George KonidarisDepartment of Computer Science Brown University, Providence, RI, USA.
Kris HauserDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, USA.
Joseph IzattDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Duke University · USBrown University · USDuke Medical Center · US

Funding

Intraoperative OCT Guidance of Intraocular SurgeryR01EY023039 · NEI · DUKE UNIVERSITY · PI IZATT, JOSEPH A, TOTH, CYNTHIA ANN · 2013 to 2016
$3.9M
Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal TransplanationR21EY029877 · NEI · DUKE UNIVERSITY · PI HAUSER, KRIS, IZATT, JOSEPH A · 2019 to 2020
$418k
NEI NIH HHS R01 EY023039NEI NIH HHS R21 EY029877
6 · The paper itself

Abstract

Ophthalmic microsurgery is technically difficult because the scale of required surgical tool manipulations challenge the limits of the surgeon's visual acuity, sensory perception, and physical dexterity. Intraoperative optical coherence tomography (OCT) imaging with micrometer-scale resolution is increasingly being used to monitor and provide enhanced real-time visualization of ophthalmic surgical maneuvers, but surgeons still face physical limitations when manipulating instruments inside the eye. Autonomously controlled robots are one avenue for overcoming these physical limitations. We demonstrate the feasibility of using learning from demonstration and reinforcement learning with an industrial robot to perform OCT-guided corneal needle insertions in an ex vivo model of deep anterior lamellar keratoplasty (DALK) surgery. Our reinforcement learning agent trained on ex vivo human corneas, then outperformed surgical fellows in reaching a target needle insertion depth in mock corneal surgery trials. This work shows the combination of learning from demonstration and reinforcement learning is a viable option for performing OCT guided robotic ophthalmic surgery.

Indexed as

Deep Learning in Robotics and AutomationLearning from DemonstrationMedical Robots and SystemsMicrosurgery

Identifiers

PMID36168513
PMCPMC9511825
OpenAlexW3016327299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.