Evidence map›Paper›PMID 36168467›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2021

Current antimicrobial prescription at outpatient dentistry centers and clinics in tertiary-care hospitals in Tokyo, Japan: A multicenter cross-sectional study.

Yasuaki Tagashira, Masao Horiuchi, Atsushi Kosaka, Takuya Washino, Mikihiro Horiuchi, Shutaro Murakami, Itoe Tagashira, Hitoshi Honda

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yasuaki TagashiraDivision of Infectious Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3736-4046
Masao HoriuchiDepartment of Infection Prevention and Control, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2424-9364
Atsushi KosakaDepartment of Infectious Diseases, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0002-5727-6599
Takuya WashinoDepartment of Infection Prevention and Control, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
Mikihiro HoriuchiDepartment of Pharmacy, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7781-9872
Shutaro MurakamiDepartment of pharmacy, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0261-3874
Itoe TagashiraDepartment of Dysphagia Rehabilitation, Tokyo Medical and Dental University, Tokyo, Japan.
Hitoshi HondaDivision of Infectious Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4870-0730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial administration is necessary before specific dental procedures to prevent postprocedural infections and complications and antimicrobials are sometimes indicated for the treatment of odontogenic infections. However, antimicrobials are commonly misused by dentists. Methods: This cross-sectional study was conducted at 4 public, tertiary-care hospitals in Tokyo, Japan, from June to July 2019. We included patients who received an antimicrobial prescription at the outpatient dentistry center or clinic at each participating hospital. The indications for antimicrobial prescription were (1) antimicrobial prescriptions for prophylaxis (APPs) or (2) antimicrobial prescriptions for treatment (APTs). Prescribing patterns were described in terms of antimicrobial choice, timing, and dosages for APPs and APTs. Results: During the study period, 1,772 patients received an antimicrobial prescription. Among them 1,439 (81.2%) were APPs and 333 (18.8%) were APTs. The most common aim of APP was to prevent local infections and complications following tooth extraction (n = 1,244, 86.4%). The proportion of appropriate APPs was only 0.8% (12 of 1,439). Among 1,439 total APPs, 171 (11.9%) were unnecessary, 32 (2.2%) were inappropriate, and 1,224 (85.1%) were suboptimal. Whereas 101 (30.3%) of 333 APTs were appropriate, the remaining 97 instances (29.1%) were unnecessary, 86 (26.7%) were inappropriate, and 46 (13.8%) were suboptimal. Conclusion: Inappropriate antimicrobial prescriptions were common among dentists in Japan. Understanding the differences in the current antimicrobial prescribing patterns for prophylaxis and treatment is critically important for implementing an effective antimicrobial stewardship program in dentistry.

Identifiers

PMID36168467
PMCPMC9495602

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