ArticleEClinicalMedicine2022
Excess diabetes mellitus-related deaths during the COVID-19 pandemic in the United States.
Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Impact of COVID-19 Pandemic on Healthcare Utilization among Patients with Type 2 Diabetes Mellitus: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- "What Can I Eat?" Healthy Choices for American Indian and Alaska Native Adults With Type 2 Diabetes: Outcomes From a Randomized Waitlist-Controlled Trial of a Diabetes Nutrition Education Program.Journal of nutrition education and behavior · 2025Trial
- Effect of COVID-19 on mortality due to diabetes mellitus in Brazil: A time series analysis from 2010 to 2023.PloS one · 2026Article
- Mortality trends in diabetes with proxy-defined steatotic liver disease in the United States, 1999-2023.Frontiers in endocrinology · 2026Article
- Indirect Impact of the COVID-19 Pandemic on All-Cause Mortality and Cardiovascular Disease Among People With Diabetes Mellitus From Korea and Hong Kong: An Interrupted Time Series Analysis.Health science reports · 2025Article
- Diabetes-related mortality in the immigrant compared to the Italian population, before and during the pandemic.Journal of endocrinological investigation · 2025Article
- Analyzing the Centers for Disease Control and Prevention Mortality Data Using Weekly Exceedance in Mortality Count and Weekly Change in Mortality Indicator: A Time Series Study.Health science reports · 2025Article
- Biopolitics at the Nexus of Chronic and Infectious Diseases.Journal of bioethical inquiry · 2025Article
- The Future Diabetes Mortality: Challenges in Meeting the 2030 Sustainable Development Goal of Reducing Premature Mortality from Diabetes.Journal of clinical medicine · 2025Article
- Changes in diabetes care and management practices during the COVID-19 pandemic.Journal of public health (Oxford, England) · 2025Article
- Diabetes exacerbates SARS-CoV-2 replication through ineffective pulmonary interferon responses, delayed cell-mediated immunity, and disruption of leptin signaling.Frontiers in cellular and infection microbiology · 2025Article
- Incidence of chronic osteomyelitis between 2016 and 2022 in a large, multicenter database in the United States.Journal of bone and joint infection · 2025Article
- Association between SARS-CoV-2 viral load and serum biomarkers with mortality in Mexican patients.Journal of education and health promotion · 2025Article
- Comprehensive assessment of COVID-19 case fatality rate and influential factors in Khuzestan Province, Iran: a two-year study.Journal of health, population, and nutrition · 2024Article
- Are we Ready for Real-Time Continuous Glucose Monitoring in the Hospital Setting? Benefits, Challenges, and Practical Approaches for Implementation : Case Vignette: Remote Real-Time Continuous Glucose Monitoring for Hospitalized Care in Quincy Koala.Current diabetes reports · 2024Review
- Trends in diabetic ketoacidosis- and hyperosmolar hyperglycemic state-related mortality during the COVID-19 pandemic in the United States: A population-based study.Journal of diabetes · 2024Article
- Modification effect of receipt of diabetes care on the association between COVID-19 infection and HbA1c level during the first year of the coronavirus pandemic using a nationwide population-based database.Journal of diabetes investigation · 2024Article
- Oxidative Stress, Endothelial Dysfunction, andAntioxidants & redox signaling · 2024Review
- Type-2 diabetes mellitus enhancesbioRxiv : the preprint server for biology · 2024Article
- Excess non-COVID-19-related mortality among inflammatory bowel disease decedents during the COVID-19 pandemic.World journal of gastroenterology · 2024Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Diabetes mellitus (DM) is a critical risk factor for severe SARS-CoV-2 infection, and SARS-CoV-2 infection contributes to worsening glycemic control. The COVID-19 pandemic profoundly disrupted the delivery of care for patients with diabetes. We aimed to determine the trend of DM-related deaths during the pandemic. Methods: In this serial population-based study between January 1, 2006 and December 31, 2021, mortality data of decedents aged ≥25 years from the National Vital Statistics System dataset was analyzed. Decedents with DM as the underlying or contributing cause of death on the death certificate were defined as DM-related deaths. Excess deaths were estimated by comparing observed versus expected age-standardized mortality rates derived from mortality during 2006-2019 with linear and polynomial regression models. The trends of mortality were quantified with joinpoint regression analysis. Subgroup analyses were performed by age, sex, race/ethnicity, and state. Findings: Among 4·25 million DM-related deaths during 2006-2021, there was a significant surge of more than 30% in mortality during the pandemic, from 106·8 (per 100,000 persons) in 2019 to 144·1 in 2020 and 148·3 in 2021. Adults aged 25-44 years had the most pronounced rise in mortality. Widened racial/ethnic disparity was observed, with Hispanics demonstrating the highest excess deaths (67·5%; 95% CI 60·9-74·7%), almost three times that of non-Hispanic whites (23·9%; 95% CI 21·2-26·7%). Interpretation: The United States saw an increase in DM-related mortality during the pandemic. The disproportionate rise in young adults and the widened racial/ethnic disparity warrant urgent preventative interventions from diverse stakeholders. Funding: National Natural Science Foundation of China.
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