Evidence map›Paper›PMID 36168240›Full record

ReviewYonsei medical journal2022

Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development.

Chang Ook Park, Hye Li Kim, Jung-Won Park

Open access · goldAbstract readReview
In one paragraph

Review in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Rethinking asthma therapy, part 2: transdermal strategies for adjunct asthma and allergy treatments.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2026
    Review
  5. Microneedles in Allergy Immunotherapy: the Present and Future.Current allergy and asthma reports · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy.Tissue engineering and regenerative medicine · 2024
    Review
  11. Construction of microneedle ofFrontiers in endocrinology · 2023
    Article
  12. Head and neck dermatitis is exacerbated byFrontiers in immunology · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chang Ook ParkDepartment of Dermatology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3856-1201
Hye Li KimDepartment of Dermatology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8574-9464
Jung-Won ParkDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0249-8749
Yonsei University · KR

Funding

Korean Health Industry Development Institute HI14C1324
6 · The paper itself

Abstract

Transdermal drug delivery systems (TDDSs) overcome the hurdle of an intact skin barrier by penetrating the skin to allow molecules through. These systems reduce side effects associated with conventional hypodermic needles. Here, we introduce novel microneedle (MN) TDDSs that enhance drug delivery by creating micron-sized pores across the skin. Many MN TDDSs designed to deliver a diverse array of therapeutics, including allergen-specific immunotherapy, skin disease treatments, and vaccines, are under pre-clinical and clinical trials. Although epicutaneous approaches are emerging as new options for treating food allergy in many clinical trials, MN TDDSs could provide a more efficient and convenient route to deliver macromolecules. Furthermore, MN TDDSs may allow for safe vaccine delivery without permanent scars. MN TDDSs are a major emerging strategy for delivering novel vaccines and treatments for diseases, including skin diseases, allergic diseases, and so on.

Indexed as

Desensitization, ImmunologicDrug Delivery SystemsSkin DiseasesVaccinesAdministration, CutaneousHumansNeedlesVaccine DevelopmentVaccinesallergen-specific immunotherapyMicroneedleskin diseasestransdermal drug delivery systemvaccines

Identifiers

PMID36168240
PMCPMC9520048
OpenAlexW4295122238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.