Evidence map›Paper›PMID 36168140›Full record

ReviewDevelopment, growth & differentiation2022

Epigenomic dynamics of early Xenopus Embryos.

Jeff Jiajing Zhou, Ken W Y Cho

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Development, growth & differentiation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The rebirth of repressive chromatin during early vertebrate development.Annals of the New York Academy of Sciences · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jeff Jiajing ZhouDevelopmental and Cell Biology, University of California, Irvine, California, USA.
Ken W Y ChoDevelopmental and Cell Biology, University of California, Irvine, California, USA.ORCID https://orcid.org/0000-0001-7282-1770

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Zygotic Genome Activation by Maternal Transcription Factors and Epigenetic ModifiersR35GM139617 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Ken W.Y. Cho · 2021 to 2026
$2.6M
Mechanisms of Foxh1 pioneer factor action during mesendoderm developmentR01GM126395 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHO, KEN W.Y. · 2017 to 2020
$1.6M
NCI NIH HHS P30 CA062203NIGMS NIH HHS R01 GM126395NIGMS NIH HHS R35 GM139617NIH HHS R01GM126395NIH HHS R35GM139617
6 · The paper itself

Abstract

How the embryonic genome regulates accessibility to transcription factors is one of the major questions in understanding the spatial and temporal dynamics of gene expression during embryogenesis. Epigenomic analyses of embryonic chromatin provide molecular insights into cell-specific gene activities and genomic architectures. In recent years, significant advances have been made to elucidate the dynamic changes behind the activation of the zygotic genome in various model organisms. Here we provide an overview of the recent epigenomic studies pertaining to early Xenopus development.

Indexed as

ChromatinEpigenomicsAnimalsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalXenopus laevisZygoteChromatin

Identifiers

PMID36168140
PMCPMC10550391

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.