Evidence map›Paper›PMID 36168047›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2023

Non-sedative cortical EEG signatures of allopregnanolone and functional comparators.

Peter M Lambert, Richard Ni, Ann Benz, Nicholas R Rensing, Michael Wong, Charles F Zorumski, Steven Mennerick

Open access · hybridAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. A Role for δ Subunit-Containing GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. New directions in neurosteroid therapeutics in neuropsychiatry.Neuroscience and biobehavioral reviews · 2025
    Review
  6. GM-1020: a novel, orally bioavailable NMDA receptor antagonist with rapid and robust antidepressant-like effects at well-tolerated doses in rodents.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  7. Article
  8. Modulators of GABANeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  9. Neurosteroids: mechanistic considerations and clinical prospects.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peter M LambertDepartment of Psychiatry, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA.ORCID 0000-0001-9427-638X
Richard NiDepartment of Psychiatry, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA.
Ann BenzDepartment of Psychiatry, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA.
Nicholas R RensingDepartment of Neurology, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA.
Michael WongDepartment of Neurology, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA.
Charles F ZorumskiDepartment of Psychiatry, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA.
Steven MennerickDepartment of Psychiatry, Washington University in St. Louis School of Medicine, 660S. Euclid Ave., MSC 8134-0181-0G, St. Louis, MO, 63110, USA. menneris@wustl.edu.ORCID 0000-0003-0868-0664
Washington University in St. Louis · US

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
Neuroactive steroids as novel psychiatric treatments: mechanistic studiesP50MH122379 · NIMH · WASHINGTON UNIVERSITY · PI COVEY, DOUGLAS F · 2021 to 2025
$12.2M
GABAA RECEPTOR POPULATIONS IN HIPPOCAMPUS AND THALAMUSR01MH123748 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2021 to 2025
$2.4M
Hippocampal circuit mechanisms of neurosteroidsF30MH126548 · NIMH · WASHINGTON UNIVERSITY · PI LAMBERT, PETER MICHAEL · 2021 to 2024
$171k
NICHD NIH HHS P50 HD103525NIMH NIH HHS F30 MH126548NIMH NIH HHS P50 MH122379NIMH NIH HHS R01 MH123748
6 · The paper itself

Abstract

Neurosteroids that positively modulate GABA

Indexed as

KetamineNeurosteroidsAnimalsAntidepressive AgentsDiazepamElectroencephalographygamma-Aminobutyric AcidHumansMicePentobarbitalPregnanoloneReceptors, GABA-AAntidepressive AgentsDiazepamgamma-Aminobutyric AcidKetamineNeurosteroidsPentobarbitalPregnanoloneReceptors, GABA-A

Identifiers

PMID36168047
PMCPMC9751067
OpenAlexW4297338201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.